Visuospatial deficits in schizophrenia: central executive and memory subsystems impairments
Object and spatial visual working memory are impaired in schizophrenic patients. It is not clear if the impairments reside in each memory subsystem alone or also in the central executive component that coordinates these processes. In order to elucidate which memory component is impaired, we develope...
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| Veröffentlicht in: | Schizophrenia research 2004-06, Vol.68 (2), p.217-223 |
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| creator | Leiderman, Eduardo A. Strejilevich, Sergio A. |
| description | Object and spatial visual working memory are impaired in schizophrenic patients. It is not clear if the impairments reside in each memory subsystem alone or also in the central executive component that coordinates these processes. In order to elucidate which memory component is impaired, we developed a paradigm with single spatial and object working memory tasks and dual ones with two different delays (5 and 30 s).
Fifteen schizophrenic patients and 14 control subjects performed these tests. Schizophrenic patients had a poorer performance compared to normal controls in all tasks and in all time delays. Both schizophrenics and controls performed significantly worse in the object task than in the spatial task. The performance was even worse in the dual task compared to the singles ones in schizophrenic patients but not in controls. These data suggest that visuospatial performance deficits in schizophrenia are due to both visuospatial memory subsystems impairments and central executive ones. The pattern of deficits observed points to a codification or evocation deficit and not to a maintenance one. |
| doi_str_mv | 10.1016/S0920-9964(03)00215-9 |
| format | Article |
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Fifteen schizophrenic patients and 14 control subjects performed these tests. Schizophrenic patients had a poorer performance compared to normal controls in all tasks and in all time delays. Both schizophrenics and controls performed significantly worse in the object task than in the spatial task. The performance was even worse in the dual task compared to the singles ones in schizophrenic patients but not in controls. These data suggest that visuospatial performance deficits in schizophrenia are due to both visuospatial memory subsystems impairments and central executive ones. The pattern of deficits observed points to a codification or evocation deficit and not to a maintenance one.</description><identifier>ISSN: 0920-9964</identifier><identifier>EISSN: 1573-2509</identifier><identifier>DOI: 10.1016/S0920-9964(03)00215-9</identifier><identifier>PMID: 15099604</identifier><language>eng</language><publisher>Amsterdam: Elsevier B.V</publisher><subject>Adult ; Adult and adolescent clinical studies ; Biological and medical sciences ; Central executive ; Cognition Disorders - diagnosis ; Cognition Disorders - physiopathology ; Female ; Form Perception - physiology ; Humans ; Male ; Medical sciences ; Memory - physiology ; Memory Disorders - diagnosis ; Memory Disorders - physiopathology ; Mental Recall - physiology ; Prefrontal Cortex - physiopathology ; Psychology. Psychoanalysis. Psychiatry ; Psychomotor Performance - physiology ; Psychopathology. Psychiatry ; Psychoses ; Reaction Time - physiology ; Schizophrenia ; Schizophrenia - diagnosis ; Schizophrenia - physiopathology ; Schizophrenic Psychology ; Space Perception - physiology ; Visuospatial ; Working memory</subject><ispartof>Schizophrenia research, 2004-06, Vol.68 (2), p.217-223</ispartof><rights>2003 Elsevier B.V.</rights><rights>2004 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c391t-a5c93fcf3e82ef50a853461db28e58b803c4f9c27af57323d7b16330c2cf9e903</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0920996403002159$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15643630$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15099604$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Leiderman, Eduardo A.</creatorcontrib><creatorcontrib>Strejilevich, Sergio A.</creatorcontrib><title>Visuospatial deficits in schizophrenia: central executive and memory subsystems impairments</title><title>Schizophrenia research</title><addtitle>Schizophr Res</addtitle><description>Object and spatial visual working memory are impaired in schizophrenic patients. It is not clear if the impairments reside in each memory subsystem alone or also in the central executive component that coordinates these processes. In order to elucidate which memory component is impaired, we developed a paradigm with single spatial and object working memory tasks and dual ones with two different delays (5 and 30 s).
Fifteen schizophrenic patients and 14 control subjects performed these tests. Schizophrenic patients had a poorer performance compared to normal controls in all tasks and in all time delays. Both schizophrenics and controls performed significantly worse in the object task than in the spatial task. The performance was even worse in the dual task compared to the singles ones in schizophrenic patients but not in controls. These data suggest that visuospatial performance deficits in schizophrenia are due to both visuospatial memory subsystems impairments and central executive ones. The pattern of deficits observed points to a codification or evocation deficit and not to a maintenance one.</description><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Biological and medical sciences</subject><subject>Central executive</subject><subject>Cognition Disorders - diagnosis</subject><subject>Cognition Disorders - physiopathology</subject><subject>Female</subject><subject>Form Perception - physiology</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Memory - physiology</subject><subject>Memory Disorders - diagnosis</subject><subject>Memory Disorders - physiopathology</subject><subject>Mental Recall - physiology</subject><subject>Prefrontal Cortex - physiopathology</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychomotor Performance - physiology</subject><subject>Psychopathology. Psychiatry</subject><subject>Psychoses</subject><subject>Reaction Time - physiology</subject><subject>Schizophrenia</subject><subject>Schizophrenia - diagnosis</subject><subject>Schizophrenia - physiopathology</subject><subject>Schizophrenic Psychology</subject><subject>Space Perception - physiology</subject><subject>Visuospatial</subject><subject>Working memory</subject><issn>0920-9964</issn><issn>1573-2509</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtv1TAQRi0EopfCTwBlA6KLlHEcJzEbhCpaKlViwWPDwnImY9UoLzxJ1cuvx7f3qmXHaqTR-eZxhHgp4VSCrN59BVNAbkxVvgV1AlBInZtHYiN1rfJCg3ksNvfIkXjG_AsApIb6qThKJbWh3IifPwKvE89uCa7POvIBw8JZGDPG6_Bnmq8jjcG9z5DGJSaEbgnXJdxQ5sYuG2iY4jbjteUtLzSk5DC7EIdE83PxxLue6cWhHovv55--nX3Or75cXJ59vMpRGbnkTqNRHr2ipiCvwTValZXs2qIh3bQNKCy9waJ2Pv1WqK5uZaUUYIHekAF1LN7s585x-r0SL3YIjNT3bqRpZVvLRmttVAL1HsQ4MUfydo5hcHFrJdidVXtn1e6UWVD2zqo1KffqsGBtB-oeUgeNCXh9AByj6310Iwb-h6tKVandpR_2HCUdN4GiZQw0InUhEi62m8J_TvkLDzqVww</recordid><startdate>20040601</startdate><enddate>20040601</enddate><creator>Leiderman, Eduardo A.</creator><creator>Strejilevich, Sergio A.</creator><general>Elsevier B.V</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20040601</creationdate><title>Visuospatial deficits in schizophrenia: central executive and memory subsystems impairments</title><author>Leiderman, Eduardo A. ; Strejilevich, Sergio A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c391t-a5c93fcf3e82ef50a853461db28e58b803c4f9c27af57323d7b16330c2cf9e903</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Adult</topic><topic>Adult and adolescent clinical studies</topic><topic>Biological and medical sciences</topic><topic>Central executive</topic><topic>Cognition Disorders - diagnosis</topic><topic>Cognition Disorders - physiopathology</topic><topic>Female</topic><topic>Form Perception - physiology</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Memory - physiology</topic><topic>Memory Disorders - diagnosis</topic><topic>Memory Disorders - physiopathology</topic><topic>Mental Recall - physiology</topic><topic>Prefrontal Cortex - physiopathology</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychomotor Performance - physiology</topic><topic>Psychopathology. Psychiatry</topic><topic>Psychoses</topic><topic>Reaction Time - physiology</topic><topic>Schizophrenia</topic><topic>Schizophrenia - diagnosis</topic><topic>Schizophrenia - physiopathology</topic><topic>Schizophrenic Psychology</topic><topic>Space Perception - physiology</topic><topic>Visuospatial</topic><topic>Working memory</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Leiderman, Eduardo A.</creatorcontrib><creatorcontrib>Strejilevich, Sergio A.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Schizophrenia research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Leiderman, Eduardo A.</au><au>Strejilevich, Sergio A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Visuospatial deficits in schizophrenia: central executive and memory subsystems impairments</atitle><jtitle>Schizophrenia research</jtitle><addtitle>Schizophr Res</addtitle><date>2004-06-01</date><risdate>2004</risdate><volume>68</volume><issue>2</issue><spage>217</spage><epage>223</epage><pages>217-223</pages><issn>0920-9964</issn><eissn>1573-2509</eissn><abstract>Object and spatial visual working memory are impaired in schizophrenic patients. It is not clear if the impairments reside in each memory subsystem alone or also in the central executive component that coordinates these processes. In order to elucidate which memory component is impaired, we developed a paradigm with single spatial and object working memory tasks and dual ones with two different delays (5 and 30 s).
Fifteen schizophrenic patients and 14 control subjects performed these tests. Schizophrenic patients had a poorer performance compared to normal controls in all tasks and in all time delays. Both schizophrenics and controls performed significantly worse in the object task than in the spatial task. The performance was even worse in the dual task compared to the singles ones in schizophrenic patients but not in controls. These data suggest that visuospatial performance deficits in schizophrenia are due to both visuospatial memory subsystems impairments and central executive ones. The pattern of deficits observed points to a codification or evocation deficit and not to a maintenance one.</abstract><cop>Amsterdam</cop><pub>Elsevier B.V</pub><pmid>15099604</pmid><doi>10.1016/S0920-9964(03)00215-9</doi><tpages>7</tpages></addata></record> |
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| ispartof | Schizophrenia research, 2004-06, Vol.68 (2), p.217-223 |
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| subjects | Adult Adult and adolescent clinical studies Biological and medical sciences Central executive Cognition Disorders - diagnosis Cognition Disorders - physiopathology Female Form Perception - physiology Humans Male Medical sciences Memory - physiology Memory Disorders - diagnosis Memory Disorders - physiopathology Mental Recall - physiology Prefrontal Cortex - physiopathology Psychology. Psychoanalysis. Psychiatry Psychomotor Performance - physiology Psychopathology. Psychiatry Psychoses Reaction Time - physiology Schizophrenia Schizophrenia - diagnosis Schizophrenia - physiopathology Schizophrenic Psychology Space Perception - physiology Visuospatial Working memory |
| title | Visuospatial deficits in schizophrenia: central executive and memory subsystems impairments |
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