Different Structural States of the Proteolipid Membrane Are Produced by Ligand Binding to the Human δ-Opioid Receptor as Shown by Plasmon-Waveguide Resonance Spectroscopy

Understanding structure-function relationships and mechanisms of signal transduction in G-protein-coupled receptors (GPCRs) is becoming increasingly important, both as a fundamental problem in membrane biology and as a consequence of their central role as pharmacological targets. Their integral memb...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Molecular pharmacology 2004-05, Vol.65 (5), p.1248-1257
Hauptverfasser:	Alves, Isabel D., Cowell, Scott M., Salamon, Zdzislaw, Devanathan, Savitha, Tollin, Gordon, Hruby, Victor J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding Sites CHO Cells Cricetinae Humans Ligands Lipid Bilayers Narcotic Antagonists - pharmacology Proteolipids - drug effects Proteolipids - metabolism Receptors, Opioid, delta - drug effects Receptors, Opioid, delta - metabolism Structure-Activity Relationship Surface Plasmon Resonance Transfection
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!