Granulocyte transmigration through the endothelium is regulated by the oxidase activity of vascular adhesion protein-1 (VAP-1)

Polymorphonuclear leukocytes (PMNs) migrate from the blood into areas of inflammation by binding to the endothelial cells of blood vessels via adhesion molecules. Vascular adhesion protein-1 (VAP-1) is one of the molecules mediating leukocyte-endothelial cell interactions. It is also an endothelial...

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Veröffentlicht in:	Blood 2004-05, Vol.103 (9), p.3388-3395
Hauptverfasser:	Koskinen, Kaisa, Vainio, Petri J., Smith, David J., Pihlavisto, Marjo, Ylä-Herttuala, Seppo, Jalkanen, Sirpa, Salmi, Marko
Format:	Artikel
Sprache:	eng
Schlagworte:	Amine Oxidase (Copper-Containing) - genetics Amine Oxidase (Copper-Containing) - metabolism Amine Oxidase (Copper-Containing) - physiology Animals Biological and medical sciences Cell Adhesion Molecules - genetics Cell Adhesion Molecules - metabolism Cell Adhesion Molecules - physiology Cell Movement Cells, Cultured Endothelium, Vascular - cytology Enzyme Inhibitors - pharmacology Fundamental and applied biological sciences. Psychology Fundamental immunology Granulocytes - cytology Humans Immunobiology Inflammation - pathology Leukocyte Rolling Male Myeloid cells: ontogeny, maturation, markers, receptors Neutrophils - cytology Perfusion Point Mutation Polynuclears Rats Rats, Sprague-Dawley Transfection Umbilical Veins - cytology
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