Expression and Function of the Vascular Endothelial Growth Factor Receptor FLT-1 in Human Eosinophils

Vascular endothelial growth factor (VEGF) is highly expressed in the airway of patients with asthma. Whether VEGF affects eosinophil function in vitro and if VEGF receptors are involved was tested. Eosinophils were from venous blood of healthy donors. Cell migration was studied by micropore filter a...

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Veröffentlicht in:	American journal of respiratory cell and molecular biology 2004-05, Vol.30 (5), p.729-735
Hauptverfasser:	Feistritzer, Clemens, Kaneider, Nicole C, Sturn, Daniel H, Mosheimer, Birgit A, Kahler, Christian M, Wiedermann, Christian J
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies - metabolism Blood Proteins - secretion Cell Movement - physiology Cells, Cultured Chemokine CCL5 - metabolism Endothelial Cells - cytology Endothelial Cells - metabolism Enzyme Inhibitors - metabolism Eosinophil Granule Proteins Eosinophils - metabolism Humans Recombinant Proteins - genetics Recombinant Proteins - metabolism Ribonucleases - secretion Signal Transduction - physiology Vascular Endothelial Growth Factor A - genetics Vascular Endothelial Growth Factor A - metabolism Vascular Endothelial Growth Factor Receptor-1 - genetics Vascular Endothelial Growth Factor Receptor-1 - metabolism Vascular Endothelial Growth Factor Receptor-2 - genetics Vascular Endothelial Growth Factor Receptor-2 - metabolism
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