Growth Hormone Improves Lean Body Mass, Physical Performance, and Quality of Life in Subjects With HIV-Associated Weight Loss or Wasting on Highly Active Antiretroviral Therapy

HIV-associated wasting is defined as ≥10% involuntary weight loss and includes declines in both lean and fat mass. This large (757 subjects), randomized, double-blind, placebo-controlled trial investigated the efficacy, safety, and tolerability of recombinant human growth hormone (rhGH) in 2 doses—0...

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Veröffentlicht in:	Journal of acquired immune deficiency syndromes (1999) 2004-04, Vol.35 (4), p.367-375
Hauptverfasser:	Moyle, Graeme J, Daar, Eric S, Gertner, Joseph M, Kotler, Donald P, Melchior, Jean-Claude, O’Brien, Fanny, Svanberg, Elisabeth
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged AIDS/HIV Antiretroviral drugs Antiretroviral Therapy, Highly Active Biological and medical sciences Body Composition - drug effects Drug Administration Schedule Exercise Tolerance - drug effects Female Fundamental and applied biological sciences. Psychology HIV HIV Wasting Syndrome - drug therapy HIV Wasting Syndrome - physiopathology Hormones Human Growth Hormone - adverse effects Human Growth Hormone - therapeutic use Human immunodeficiency virus Human viral diseases Humans Infectious diseases Male Medical sciences Microbiology Middle Aged Miscellaneous Quality of Life Recombinant Proteins - adverse effects Recombinant Proteins - therapeutic use Viral diseases Virology Weight Weight Gain - drug effects
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