Effects of Losartan and Simvastatin on Monocyte-Derived Microparticles in Hypertensive Patients With and Without Type 2 Diabetes Mellitus

Monocyte-derived microparticles play an important role in the pathogenesis of diabetic vasculopathy, and angiotensin II receptor blocker and statin have been shown to have a beneficial effect on the angiopathies of hypertension and hyperglycemia in patients with type 2 diabetes mellitus. However, th...

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Veröffentlicht in:	Clinical and applied thrombosis/hemostasis 2004-04, Vol.10 (2), p.133-141
Hauptverfasser:	Nomura, Shosaku, Shouzu, Akira, Omoto, Seitaro, Nishikawa, Mitsushige, Iwasaka, Toshiji
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Angiotensin Receptor Antagonists Biomarkers - analysis Biomarkers - blood Blood Pressure - drug effects Chemokines Chemokines - blood Diabetes Diabetes Complications Diabetes Mellitus - drug therapy Female Glucose Humans Hypertension Hypertension - complications Hypertension - drug therapy Losartan - administration & dosage Losartan - pharmacology Male Middle Aged Monocytes - drug effects Monocytes - metabolism Receptors, Angiotensin - metabolism Simvastatin - administration & dosage Simvastatin - pharmacology
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