Follow-up Study of Aortic-Valve Replacement Surgery in Patients With Takayasu's Disease Complicated by Aortic Regurgitation
Aortic regurgitation (AR) is not a rare complication of Takayasu's disease and is now considered as an important risk factor related to mortality. Aortic-valve replacement surgery is the only curative treatment, but cardiac function and mortality after surgery have not been reported, so a follo...
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| Veröffentlicht in: | Circulation Journal 2002, Vol.66(6), pp.564-566 |
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| container_title | Circulation Journal |
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| creator | Nishimura, Satoshi Toubaru, Tetsuya Ootaki, Eiji Sumiyoshi, Tetsuya |
| description | Aortic regurgitation (AR) is not a rare complication of Takayasu's disease and is now considered as an important risk factor related to mortality. Aortic-valve replacement surgery is the only curative treatment, but cardiac function and mortality after surgery have not been reported, so a follow-up study in 10 patients with Takayasu's disease complicated by AR was performed. Six patients underwent aortic-valve replacement surgery and all had improvement of the ejection fraction and a decrease in the size of the left ventricle size on echocardiography. Three of the 6 cases had a remote cardiovascular event. Detailed pathological examination carried out in one case of the aortic valve and aortic specimen from surgery showed only lymphoid cell infiltration around the capillary in the ascending aorta, and no other inflammatory change. Inflammation was well controlled at surgery by pre-operative steroid therapy, so early and aggressive aortic-valve replacement surgery with peri-operative immunosuppressive therapy should be considered for patients with Takayasu's disease. (Circ J 2002; 66: 564 - 566) |
| doi_str_mv | 10.1253/circj.66.564 |
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Aortic-valve replacement surgery is the only curative treatment, but cardiac function and mortality after surgery have not been reported, so a follow-up study in 10 patients with Takayasu's disease complicated by AR was performed. Six patients underwent aortic-valve replacement surgery and all had improvement of the ejection fraction and a decrease in the size of the left ventricle size on echocardiography. Three of the 6 cases had a remote cardiovascular event. Detailed pathological examination carried out in one case of the aortic valve and aortic specimen from surgery showed only lymphoid cell infiltration around the capillary in the ascending aorta, and no other inflammatory change. Inflammation was well controlled at surgery by pre-operative steroid therapy, so early and aggressive aortic-valve replacement surgery with peri-operative immunosuppressive therapy should be considered for patients with Takayasu's disease. 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Graft diseases ; Surgery of the heart ; Takayasu Arteritis - complications ; Takayasu Arteritis - pathology ; Takayasu Arteritis - surgery ; Takayasu's disease ; Time Factors ; Treatment Outcome ; Ventricular Function, Left - physiology</subject><ispartof>Circulation Journal, 2002, Vol.66(6), pp.564-566</ispartof><rights>2002 THE JAPANESE CIRCULATION SOCIETY</rights><rights>2002 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c503t-4c381e1918aa09d7abf08f0ac2d18d40ff016353eb8109c8d42d1a4313d61b3d3</citedby><cites>FETCH-LOGICAL-c503t-4c381e1918aa09d7abf08f0ac2d18d40ff016353eb8109c8d42d1a4313d61b3d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1877,4010,27900,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=13858642$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12074274$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nishimura, Satoshi</creatorcontrib><creatorcontrib>Toubaru, Tetsuya</creatorcontrib><creatorcontrib>Ootaki, Eiji</creatorcontrib><creatorcontrib>Sumiyoshi, Tetsuya</creatorcontrib><title>Follow-up Study of Aortic-Valve Replacement Surgery in Patients With Takayasu's Disease Complicated by Aortic Regurgitation</title><title>Circulation Journal</title><addtitle>Circ J</addtitle><description>Aortic regurgitation (AR) is not a rare complication of Takayasu's disease and is now considered as an important risk factor related to mortality. Aortic-valve replacement surgery is the only curative treatment, but cardiac function and mortality after surgery have not been reported, so a follow-up study in 10 patients with Takayasu's disease complicated by AR was performed. Six patients underwent aortic-valve replacement surgery and all had improvement of the ejection fraction and a decrease in the size of the left ventricle size on echocardiography. Three of the 6 cases had a remote cardiovascular event. Detailed pathological examination carried out in one case of the aortic valve and aortic specimen from surgery showed only lymphoid cell infiltration around the capillary in the ascending aorta, and no other inflammatory change. Inflammation was well controlled at surgery by pre-operative steroid therapy, so early and aggressive aortic-valve replacement surgery with peri-operative immunosuppressive therapy should be considered for patients with Takayasu's disease. (Circ J 2002; 66: 564 - 566)</description><subject>Adult</subject><subject>Aorta</subject><subject>Aortic regurgitation</subject><subject>Aortic Valve Insufficiency - complications</subject><subject>Aortic valve replacement</subject><subject>Aortitis syndrome</subject><subject>Biological and medical sciences</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Heart Valve Prosthesis Implantation</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Retrospective Studies</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the heart</subject><subject>Takayasu Arteritis - complications</subject><subject>Takayasu Arteritis - pathology</subject><subject>Takayasu Arteritis - surgery</subject><subject>Takayasu's disease</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><subject>Ventricular Function, Left - physiology</subject><issn>1346-9843</issn><issn>1347-4820</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkEFv1DAQRiMEoqVw44x8AS5ksWPHcY6rhQJSJRAtcIwmzmTrxYmD7YAi_jxuN2IvtjXz_D7py7LnjG5YUfK32nh92Ei5KaV4kJ0zLqpcqII-vH_LvFaCn2VPQjhQWtS0rB9nZ6yglSgqcZ79vXTWuj_5PJHrOHcLcT3ZOh-Nzr-D_Y3kK04WNA44RnI9-z36hZiRfIFo0iiQHybekhv4CQuE-XUg70xACEh2bpis0RCxI-2yOpNtnxwmpt9ufJo96sEGfLbeF9m3y_c3u4_51ecPn3bbq1yXlMdcaK4YspopAFp3FbQ9VT0FXXRMdYL2PWWSlxxbxWit0ygtQHDGO8la3vGL7NXRO3n3a8YQm8EEjdbCiG4OTcVUSqhoAt8cQe1dCB77ZvJmAL80jDZ3ZTf3ZTdSNqnshL9YvXM7YHeC13YT8HIFIGiwvYdRm3DiuCqVFEXitkfuECLs8T8Ad51ZPKXK45HCT7tb8A2O_B-eraFd</recordid><startdate>2002</startdate><enddate>2002</enddate><creator>Nishimura, Satoshi</creator><creator>Toubaru, Tetsuya</creator><creator>Ootaki, Eiji</creator><creator>Sumiyoshi, Tetsuya</creator><general>The Japanese Circulation Society</general><general>Japanese Circulation Society</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2002</creationdate><title>Follow-up Study of Aortic-Valve Replacement Surgery in Patients With Takayasu's Disease Complicated by Aortic Regurgitation</title><author>Nishimura, Satoshi ; Toubaru, Tetsuya ; Ootaki, Eiji ; Sumiyoshi, Tetsuya</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c503t-4c381e1918aa09d7abf08f0ac2d18d40ff016353eb8109c8d42d1a4313d61b3d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Adult</topic><topic>Aorta</topic><topic>Aortic regurgitation</topic><topic>Aortic Valve Insufficiency - complications</topic><topic>Aortic valve replacement</topic><topic>Aortitis syndrome</topic><topic>Biological and medical sciences</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Heart Valve Prosthesis Implantation</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Retrospective Studies</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the heart</topic><topic>Takayasu Arteritis - complications</topic><topic>Takayasu Arteritis - pathology</topic><topic>Takayasu Arteritis - surgery</topic><topic>Takayasu's disease</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><topic>Ventricular Function, Left - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nishimura, Satoshi</creatorcontrib><creatorcontrib>Toubaru, Tetsuya</creatorcontrib><creatorcontrib>Ootaki, Eiji</creatorcontrib><creatorcontrib>Sumiyoshi, Tetsuya</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Circulation Journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nishimura, Satoshi</au><au>Toubaru, Tetsuya</au><au>Ootaki, Eiji</au><au>Sumiyoshi, Tetsuya</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Follow-up Study of Aortic-Valve Replacement Surgery in Patients With Takayasu's Disease Complicated by Aortic Regurgitation</atitle><jtitle>Circulation Journal</jtitle><addtitle>Circ J</addtitle><date>2002</date><risdate>2002</risdate><volume>66</volume><issue>6</issue><spage>564</spage><epage>566</epage><pages>564-566</pages><issn>1346-9843</issn><eissn>1347-4820</eissn><abstract>Aortic regurgitation (AR) is not a rare complication of Takayasu's disease and is now considered as an important risk factor related to mortality. Aortic-valve replacement surgery is the only curative treatment, but cardiac function and mortality after surgery have not been reported, so a follow-up study in 10 patients with Takayasu's disease complicated by AR was performed. Six patients underwent aortic-valve replacement surgery and all had improvement of the ejection fraction and a decrease in the size of the left ventricle size on echocardiography. Three of the 6 cases had a remote cardiovascular event. Detailed pathological examination carried out in one case of the aortic valve and aortic specimen from surgery showed only lymphoid cell infiltration around the capillary in the ascending aorta, and no other inflammatory change. Inflammation was well controlled at surgery by pre-operative steroid therapy, so early and aggressive aortic-valve replacement surgery with peri-operative immunosuppressive therapy should be considered for patients with Takayasu's disease. (Circ J 2002; 66: 564 - 566)</abstract><cop>Kyoto</cop><pub>The Japanese Circulation Society</pub><pmid>12074274</pmid><doi>10.1253/circj.66.564</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adult Aorta Aortic regurgitation Aortic Valve Insufficiency - complications Aortic valve replacement Aortitis syndrome Biological and medical sciences Female Follow-Up Studies Heart Valve Prosthesis Implantation Humans Male Medical sciences Middle Aged Retrospective Studies Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the heart Takayasu Arteritis - complications Takayasu Arteritis - pathology Takayasu Arteritis - surgery Takayasu's disease Time Factors Treatment Outcome Ventricular Function, Left - physiology |
| title | Follow-up Study of Aortic-Valve Replacement Surgery in Patients With Takayasu's Disease Complicated by Aortic Regurgitation |
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