Immune Sensitization in the Skin Is Enhanced by Antigen-Independent Effects of IgE

Contact sensitivity responses require both effective immune sensitization following cutaneous exposure to chemical haptens and antigen-specific elicitation of inflammation upon subsequent hapten challenge. We report that antigen-independent effects of IgE antibodies can promote immune sensitization...

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Veröffentlicht in:	Immunity (Cambridge, Mass.) Mass.), 2004-04, Vol.20 (4), p.381-392
Hauptverfasser:	Bryce, Paul J, Miller, Mendy L, Miyajima, Ichiro, Tsai, Mindy, Galli, Stephen J, Oettgen, Hans C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - pharmacology Adoptive Transfer Allergies Animals B-Lymphocytes - immunology Cell Movement - immunology Cytokines Defects Dendritic Cells - immunology Dermatitis, Contact - immunology Gene expression Haptens - immunology Immunization Immunoglobulin E - blood Immunoglobulin E - immunology Mast Cells - immunology Mice Oxazolone - pharmacology Receptors, IgE - immunology Reverse Transcriptase Polymerase Chain Reaction Skin Skin - drug effects Skin - immunology Skin - pathology Variance analysis
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