Functional role for cannabinoids in respiratory stability during sleep

Serotonin, acting in the peripheral nervous system, can exacerbate sleep-related apnea, and systemically administered serotonin antagonists reduce sleep-disordered respiration in rats and bulldogs. Because cannabinoid receptor agonists are known to inhibit the excitatory effects of serotonin on nodo...

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Veröffentlicht in:	Sleep (New York, N.Y.) N.Y.), 2002-06, Vol.25 (4), p.391-398
Hauptverfasser:	CARLEY, David W, PAVLOVIC, Sasa, JANELIDZE, Marika, RADULOVACKI, Miodrag
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Behavioral psychophysiology Biological and medical sciences Cannabinoid Receptor Modulators Cannabinoids - pharmacology Cannabinoids - therapeutic use Cross-Over Studies Electroencephalography Electromyography - drug effects Fundamental and applied biological sciences. Psychology Male Muscle, Skeletal Neurotransmission and behavior Polysomnography - methods Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rats Rats, Sprague-Dawley Respiration - drug effects Scalp Sleep Apnea Syndromes - drug therapy Sleep, REM - drug effects Sleep. Vigilance Time Factors Vertebrates: nervous system and sense organs Wakefulness - drug effects
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