Effects of the mono- and tetrasialogangliosides GM1 and GQ1b on ATP-induced long-term potentiation in hippocampal CA1 neurons

The effects of the mono- and tetrasialogangliosides, GM1 and GQ1b, on ATP-induced long-term potentiation (LTP) were studied in CA1 neurons of guinea pig hippocampal slices. Application of 5 or 10 µM ATP for 10 min resulted in a transient depression followed by a slow augmentation of synaptic transmi...

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Veröffentlicht in:	Glycobiology (Oxford) 2002-05, Vol.12 (5), p.339-344
Hauptverfasser:	Fujii, Satoshi, Igarashi, Kotaro, Sasaki, Hiroshi, Furuse, Hidekazu, Ito, Ken-ichi, Kaneko, Kenya, Kato, Hiroshi, Inokuchi, Jin-ichi, Waki, Hatsue, Ando, Susumu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - pharmacology Animals G(M1) Ganglioside - pharmacology Gangliosides - pharmacology Guinea Pigs Hippocampus - cytology Hippocampus - drug effects Hippocampus - physiology In Vitro Techniques Key words: ATP/ecto-protein kinase/GM1 and GQ1b/hippocampus/long-term potentiation Long-Term Potentiation - drug effects Male Neurons - drug effects Neurons - physiology
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