In vitro Effects of Some Steroidal Hormones on the Replication of Avian Pneumovirus
The effects of testosterone, oestradiol, progesterone and cortisone on the in vitro replication of avian pneumovirus in tracheal organ cultures (TOC) were investigated. Samples of cell‐associated and cell‐free virus from TOC, grown in medium containing these hormones, were taken at selected interval...
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| Veröffentlicht in: | Journal of veterinary medicine. Series B 2002-05, Vol.49 (4), p.193-196 |
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| container_end_page | 196 |
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| container_issue | 4 |
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| container_title | Journal of veterinary medicine. Series B |
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| creator | AL-AFALEQ, A. I. JONES, R. C. HOMEIDA, A. M. SAVAGE, C. E. |
| description | The effects of testosterone, oestradiol, progesterone and cortisone on the in vitro replication of avian pneumovirus in tracheal organ cultures (TOC) were investigated. Samples of cell‐associated and cell‐free virus from TOC, grown in medium containing these hormones, were taken at selected intervals. Progesterone and cortisone caused a slight increase in cell‐associated virus. Testosterone and oestradiol caused a slight delay and decrease in virus replication when compared with the controls. All groups shared the same time interval to reach peak cell‐free virus titre, 96 h post inoculation. In comparison with the controls, only a small drop (0.25–0.50 log10) in the peak of virus titre was observed in the hormone treated groups. |
| doi_str_mv | 10.1046/j.1439-0450.2002.00501.x |
| format | Article |
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| ispartof | Journal of veterinary medicine. Series B, 2002-05, Vol.49 (4), p.193-196 |
| issn | 0931-1793 1439-0450 |
| language | eng |
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| source | MEDLINE; Wiley Journals |
| subjects | Animals Cortisone - pharmacology Estradiol - pharmacology Pneumovirus - drug effects Pneumovirus - physiology Progesterone - pharmacology Steroids - pharmacology Testosterone - pharmacology Trachea - microbiology Virus Replication - drug effects |
| title | In vitro Effects of Some Steroidal Hormones on the Replication of Avian Pneumovirus |
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