Curettage of Giant Congenital Melanocytic Nevi in Neonates: A Decade Later
BACKGROUND Currently, there is tremendous uncertainty regarding how giant congenital melanocytic nevi (GCMN) should be treated. Our approach to patients with GCMN is based on 2 main considerations: (1) obtain an acceptable cosmetic result to decrease the psychosocial inconvenience to the patient, an...
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| Veröffentlicht in: | Archives of dermatology (1960) 2002-07, Vol.138 (7), p.943-947 |
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| creator | De Raeve, Linda E Roseeuw, Diane I |
| description | BACKGROUND Currently, there is tremendous uncertainty regarding how giant congenital melanocytic nevi (GCMN) should be treated. Our approach to patients with GCMN is based on 2 main considerations: (1) obtain an acceptable cosmetic result to decrease the psychosocial inconvenience to the patient, and (2) attempt to minimize the risk of malignancy. For the past 10 years we have treated GCMN by curettage in the neonatal period. We report our experience and results. OBSERVATIONS Sixteen neonates with GCMN were treated by curettage between 1990 and 2000. Biopsy specimens were obtained and the patients received close clinical follow-up. In most patients cosmetic and functional results were good, and, to date, no melanoma has been observed in this series. CONCLUSIONS Curettage offers an adequate alternative to surgical excision when performed during the first 2 weeks of life. Patients and parents are pleased with the cosmetic and functional results and thereby suffer less from the psychosocial inconvenience caused by these lesions. Careful long-term follow-up of these children is essential to monitor final cosmetic outcome and reduce the potential for malignancy.Arch Dermatol. 2002;138:943-948--> |
| doi_str_mv | 10.1001/archderm.138.7.943 |
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Our approach to patients with GCMN is based on 2 main considerations: (1) obtain an acceptable cosmetic result to decrease the psychosocial inconvenience to the patient, and (2) attempt to minimize the risk of malignancy. For the past 10 years we have treated GCMN by curettage in the neonatal period. We report our experience and results. OBSERVATIONS Sixteen neonates with GCMN were treated by curettage between 1990 and 2000. Biopsy specimens were obtained and the patients received close clinical follow-up. In most patients cosmetic and functional results were good, and, to date, no melanoma has been observed in this series. CONCLUSIONS Curettage offers an adequate alternative to surgical excision when performed during the first 2 weeks of life. Patients and parents are pleased with the cosmetic and functional results and thereby suffer less from the psychosocial inconvenience caused by these lesions. Careful long-term follow-up of these children is essential to monitor final cosmetic outcome and reduce the potential for malignancy.Arch Dermatol. 2002;138:943-948--></description><identifier>ISSN: 0003-987X</identifier><identifier>ISSN: 2168-6068</identifier><identifier>EISSN: 1538-3652</identifier><identifier>EISSN: 2168-6084</identifier><identifier>DOI: 10.1001/archderm.138.7.943</identifier><identifier>PMID: 12071822</identifier><identifier>CODEN: ARDEAC</identifier><language>eng</language><publisher>Chicago, IL: American Medical Association</publisher><subject>Antigens, Neoplasm ; Biological and medical sciences ; Child, Preschool ; Curettage ; Dermatologic Surgical Procedures ; Dermatology ; Female ; Follow-Up Studies ; Humans ; Infant ; Infant, Newborn ; Male ; Medical sciences ; Melanoma-Specific Antigens ; Neoplasm Proteins - analysis ; Nevus, Pigmented - congenital ; Nevus, Pigmented - pathology ; Nevus, Pigmented - surgery ; Pigmentary diseases of the skin ; Skin - pathology ; Skin Neoplasms - congenital ; Skin Neoplasms - pathology ; Skin Neoplasms - surgery ; Skin plastic surgery ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Treatment Outcome ; Wound Healing - physiology</subject><ispartof>Archives of dermatology (1960), 2002-07, Vol.138 (7), p.943-947</ispartof><rights>2002 INIST-CNRS</rights><rights>Copyright American Medical Association Jul 2002</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://jamanetwork.com/journals/jamadermatology/articlepdf/10.1001/archderm.138.7.943$$EPDF$$P50$$Gama$$H</linktopdf><linktohtml>$$Uhttps://jamanetwork.com/journals/jamadermatology/fullarticle/10.1001/archderm.138.7.943$$EHTML$$P50$$Gama$$H</linktohtml><link.rule.ids>64,314,776,780,3326,27903,27904,76236,76239</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=13761088$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12071822$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>De Raeve, Linda E</creatorcontrib><creatorcontrib>Roseeuw, Diane I</creatorcontrib><title>Curettage of Giant Congenital Melanocytic Nevi in Neonates: A Decade Later</title><title>Archives of dermatology (1960)</title><addtitle>Arch Dermatol</addtitle><description>BACKGROUND Currently, there is tremendous uncertainty regarding how giant congenital melanocytic nevi (GCMN) should be treated. Our approach to patients with GCMN is based on 2 main considerations: (1) obtain an acceptable cosmetic result to decrease the psychosocial inconvenience to the patient, and (2) attempt to minimize the risk of malignancy. For the past 10 years we have treated GCMN by curettage in the neonatal period. We report our experience and results. OBSERVATIONS Sixteen neonates with GCMN were treated by curettage between 1990 and 2000. Biopsy specimens were obtained and the patients received close clinical follow-up. In most patients cosmetic and functional results were good, and, to date, no melanoma has been observed in this series. CONCLUSIONS Curettage offers an adequate alternative to surgical excision when performed during the first 2 weeks of life. Patients and parents are pleased with the cosmetic and functional results and thereby suffer less from the psychosocial inconvenience caused by these lesions. Careful long-term follow-up of these children is essential to monitor final cosmetic outcome and reduce the potential for malignancy.Arch Dermatol. 2002;138:943-948--></description><subject>Antigens, Neoplasm</subject><subject>Biological and medical sciences</subject><subject>Child, Preschool</subject><subject>Curettage</subject><subject>Dermatologic Surgical Procedures</subject><subject>Dermatology</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Melanoma-Specific Antigens</subject><subject>Neoplasm Proteins - analysis</subject><subject>Nevus, Pigmented - congenital</subject><subject>Nevus, Pigmented - pathology</subject><subject>Nevus, Pigmented - surgery</subject><subject>Pigmentary diseases of the skin</subject><subject>Skin - pathology</subject><subject>Skin Neoplasms - congenital</subject><subject>Skin Neoplasms - pathology</subject><subject>Skin Neoplasms - surgery</subject><subject>Skin plastic surgery</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Treatment Outcome</subject><subject>Wound Healing - physiology</subject><issn>0003-987X</issn><issn>2168-6068</issn><issn>1538-3652</issn><issn>2168-6084</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkE1v1DAQhi0EokvhB8ABWUhwy-LxxLHDrVqgH1rgAhI3azaelFT5KHaC1H-PV7u0EqeR5ecdv36EeAVqDUrBe4rNr8BxWAO6tV3XJT4SKzDoCqyMfixWSiksamd_nohnKd3kjHZOPxUnoJUFp_VKXG2WyPNM1yynVp53NM5yM43XPHYz9fIL9zROzd3cNfIr_-lkN-Y5jTRz-iDP5EduKLDc5nN8Lp601Cd-cZyn4sfnT983F8X22_nl5mxbEGozF8apUEGFO6Ur2Flb7lrWba6qAjHY1pgAjCqUVKNGsIo4OFNBW9e2chDwVLw77L2N0--F0-yHLjXc56Y8Lcnvf1YaNBl88x94My1xzN28RgStS3QZ0geoiVNKkVt_G7uB4p0H5fea_T_NPmv21mfNOfT6uHnZDRweIkevGXh7BCg11LeRxqZLDxzaCpTbv_7ywNFA97eldc6V-BcjAY0b</recordid><startdate>20020701</startdate><enddate>20020701</enddate><creator>De Raeve, Linda E</creator><creator>Roseeuw, Diane I</creator><general>American Medical Association</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20020701</creationdate><title>Curettage of Giant Congenital Melanocytic Nevi in Neonates: A Decade Later</title><author>De Raeve, Linda E ; Roseeuw, Diane I</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a325t-580d6163b0261b774bfe2f0000dae17f55d1e30d4a9323170aed8561f997681d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Antigens, Neoplasm</topic><topic>Biological and medical sciences</topic><topic>Child, Preschool</topic><topic>Curettage</topic><topic>Dermatologic Surgical Procedures</topic><topic>Dermatology</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Melanoma-Specific Antigens</topic><topic>Neoplasm Proteins - analysis</topic><topic>Nevus, Pigmented - congenital</topic><topic>Nevus, Pigmented - pathology</topic><topic>Nevus, Pigmented - surgery</topic><topic>Pigmentary diseases of the skin</topic><topic>Skin - pathology</topic><topic>Skin Neoplasms - congenital</topic><topic>Skin Neoplasms - pathology</topic><topic>Skin Neoplasms - surgery</topic><topic>Skin plastic surgery</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Treatment Outcome</topic><topic>Wound Healing - physiology</topic><toplevel>online_resources</toplevel><creatorcontrib>De Raeve, Linda E</creatorcontrib><creatorcontrib>Roseeuw, Diane I</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of dermatology (1960)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>De Raeve, Linda E</au><au>Roseeuw, Diane I</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Curettage of Giant Congenital Melanocytic Nevi in Neonates: A Decade Later</atitle><jtitle>Archives of dermatology (1960)</jtitle><addtitle>Arch Dermatol</addtitle><date>2002-07-01</date><risdate>2002</risdate><volume>138</volume><issue>7</issue><spage>943</spage><epage>947</epage><pages>943-947</pages><issn>0003-987X</issn><issn>2168-6068</issn><eissn>1538-3652</eissn><eissn>2168-6084</eissn><coden>ARDEAC</coden><abstract>BACKGROUND Currently, there is tremendous uncertainty regarding how giant congenital melanocytic nevi (GCMN) should be treated. Our approach to patients with GCMN is based on 2 main considerations: (1) obtain an acceptable cosmetic result to decrease the psychosocial inconvenience to the patient, and (2) attempt to minimize the risk of malignancy. For the past 10 years we have treated GCMN by curettage in the neonatal period. We report our experience and results. OBSERVATIONS Sixteen neonates with GCMN were treated by curettage between 1990 and 2000. Biopsy specimens were obtained and the patients received close clinical follow-up. In most patients cosmetic and functional results were good, and, to date, no melanoma has been observed in this series. CONCLUSIONS Curettage offers an adequate alternative to surgical excision when performed during the first 2 weeks of life. Patients and parents are pleased with the cosmetic and functional results and thereby suffer less from the psychosocial inconvenience caused by these lesions. Careful long-term follow-up of these children is essential to monitor final cosmetic outcome and reduce the potential for malignancy.Arch Dermatol. 2002;138:943-948--></abstract><cop>Chicago, IL</cop><pub>American Medical Association</pub><pmid>12071822</pmid><doi>10.1001/archderm.138.7.943</doi><tpages>5</tpages></addata></record> |
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| subjects | Antigens, Neoplasm Biological and medical sciences Child, Preschool Curettage Dermatologic Surgical Procedures Dermatology Female Follow-Up Studies Humans Infant Infant, Newborn Male Medical sciences Melanoma-Specific Antigens Neoplasm Proteins - analysis Nevus, Pigmented - congenital Nevus, Pigmented - pathology Nevus, Pigmented - surgery Pigmentary diseases of the skin Skin - pathology Skin Neoplasms - congenital Skin Neoplasms - pathology Skin Neoplasms - surgery Skin plastic surgery Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Treatment Outcome Wound Healing - physiology |
| title | Curettage of Giant Congenital Melanocytic Nevi in Neonates: A Decade Later |
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