p53-dependent expression of the stress-induced protein (SIP)

The mouse stress-induced protein (SIP) mRNA is activated in the pancreas with acute pancreatitis and in several cell lines in response to various stress agents. The SIP gene is alternatively spliced, generating two proteins (SIP 18 and SIP 27). Both proteins, located mainly in the nucleus, promote c...

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Veröffentlicht in:	European journal of cell biology 2002-05, Vol.81 (5), p.294-301
Hauptverfasser:	Tomasini, Richard, Azizi Samir, Amina, Pebusque, Marie-Josèphe, Calvo, Ezequiel L., Totaro, Serena, Dagorn, Jean Charles, Dusetti, Nelson J., Iovanna, Juan L.
Format:	Artikel
Sprache:	eng
Schlagworte:	alternative splicing - transformation Amino Acid Sequence Animals Antineoplastic Agents - metabolism Carrier Proteins - genetics Carrier Proteins - metabolism Cell Transformation, Neoplastic Cells, Cultured cellular stress Cloning, Molecular Doxorubicin - metabolism Fibroblasts - cytology Fibroblasts - physiology Gene Expression Regulation, Neoplastic Genes, Reporter Heat-Shock Proteins - genetics Heat-Shock Proteins - metabolism Humans Mice Molecular Sequence Data Mutation p53 Promoter Regions, Genetic ras Proteins - genetics ras Proteins - metabolism Sequence Alignment SIP Tissue Distribution Transcription, Genetic Tumor Suppressor Protein p53 - genetics Tumor Suppressor Protein p53 - metabolism
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