Safety, Immunogenicity, and Efficacy of Two Escherichia coli cya crp Mutants as Vaccines for Broilers

Attenuated derivatives (Δcya Δcrp mutants) of an O2 and an O78 avian septicemic Escherichia coli strain were used to immunize broiler chickens by spray to determine the safety, immunogenicity, and efficacy of the derivatives in single- and double-dose regimens. In the safety and immunogenicity studi...

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Veröffentlicht in:	Avian diseases 2002-04, Vol.46 (2), p.287-297
Hauptverfasser:	Peighambari, S. M, Hunter, D. B, Shewen, P. E, Gyles, C. L
Format:	Artikel
Sprache:	eng
Schlagworte:	Aerosols Air Sacs - immunology Air Sacs - microbiology Animals Antibodies broiler chickens Chickens crp cya disease resistance dosage Dose-Response Relationship, Immunologic efficacy Escherichia coli Escherichia coli - genetics Escherichia coli - immunology Escherichia coli - pathogenicity Escherichia coli Infections - pathology Escherichia coli Infections - prevention & control Escherichia coli Infections - veterinary Escherichia coli Vaccines - genetics Escherichia coli Vaccines - immunology experimental infections Immune response immunogenicity Immunoglobulin A - blood immunoglobulin G Immunoglobulin G - blood Infections Lesions mortality mutants Mutation pathological processes and conditions poultry Poultry Diseases - pathology Poultry Diseases - prevention & control Pulmonary alveoli Random Allocation Regular s Safety Treatment Outcome Vaccination Vaccines, Attenuated - immunology Virulence - genetics Washing
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