Histopathologic effects of neoadjuvant therapies for advanced squamous cell carcinoma of the esophagus: multivariate analysis of predictive factors and p53 overexpression

In 97 patients (60, chemotherapy; 22, chemoradiotherapy; 15, radiotherapy), histopathologic effects were evaluated microscopically, and histologic response rates were compared among three neoadjuvant treatment modalities. Predictive factors for neoadjuvant therapies were analyzed by logistic regress...

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Veröffentlicht in:	Diseases of the esophagus 2002-03, Vol.15 (1), p.61-66
Hauptverfasser:	Kajiyama, Y., Hattori, K., Tomita, N., Amano, T., Iwanuma, Y., Narumi, K., Udagawa, H., Tsurumaru, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic Combined Chemotherapy Protocols - administration & dosage Biomarkers, Tumor - analysis Biopsy, Needle Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - mortality Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - therapy Combined Modality Therapy Esophageal Neoplasms - genetics Esophageal Neoplasms - mortality Esophageal Neoplasms - pathology Esophageal Neoplasms - therapy Esophagectomy - methods Female Gene Expression Genes, p53 - genetics Humans Immunohistochemistry Logistic Models Male Middle Aged Multivariate Analysis Neoadjuvant Therapy - methods Neoplasm Staging Predictive Value of Tests Prognosis Prospective Studies Sensitivity and Specificity Severity of Illness Index Survival Rate
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