α, β-unsaturated 4-oxo acids in heterocylic synthesis. II. Behavior of 3-(1,1-Dioxadibenzothein-4-oyl)acrylic acid towards carbon nucleophiles under Michael reaction condition

3-(1,1-Dioxadibenzothien-4-oyl)acrylic acid (1) was condensed with compounds containing active methylene groups under Michael reaction conditions to furnish the Michael adducts (lactones 2a-c, lactams 3a-c, ketones 4a,b). The behavior of these adducts toward the action of hydrazine hydrate were inve...

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Veröffentlicht in:	Folia microbiologica 2002, Vol.47 (2), p.131-136
Hauptverfasser:	WASFY, A. A. F, AMINE, M. S, ARIEF, M. M. H, DONIA, S. G, ALY, A. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrylates - chemical synthesis Acrylates - chemistry Acrylates - pharmacology Bacteria - drug effects Carboxylic Acids - chemical synthesis Carboxylic Acids - chemistry Carboxylic Acids - pharmacology Chemistry Exact sciences and technology Heterocyclic compounds Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings Microbial Sensitivity Tests Organic chemistry Preparations and properties Spectrum Analysis
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Zusammenfassung:	3-(1,1-Dioxadibenzothien-4-oyl)acrylic acid (1) was condensed with compounds containing active methylene groups under Michael reaction conditions to furnish the Michael adducts (lactones 2a-c, lactams 3a-c, ketones 4a,b). The behavior of these adducts toward the action of hydrazine hydrate were investigated. The compounds were tested for their biological properties.
ISSN:	0015-5632 1874-9356
DOI:	10.1007/BF02817670