Centrosome Maturation and Duplication in C. elegans Require the Coiled-Coil Protein SPD-2

Centrosomes are major determinants of mitotic spindle structure, but the mechanisms regulating their behavior remain poorly understood. The spd-2 gene of C. elegans is required for centrosome assembly or “maturation.” Here we show that spd-2 encodes a coiled-coil protein that localizes within perice...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Developmental cell 2004-04, Vol.6 (4), p.511-523
Hauptverfasser:	Kemp, Catherine A, Kopish, Kevin R, Zipperlen, Peder, Ahringer, Julie, O'Connell, Kevin F
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence - genetics Animals Aurora Kinases Base Sequence - genetics Caenorhabditis elegans Caenorhabditis elegans - genetics Caenorhabditis elegans - metabolism Caenorhabditis elegans Proteins - genetics Caenorhabditis elegans Proteins - isolation & purification Caenorhabditis elegans Proteins - metabolism Cell Cycle Proteins Cell Differentiation - genetics Centrioles - genetics Centrioles - metabolism Centrosome - metabolism DNA, Complementary - analysis DNA, Complementary - genetics Dyneins - genetics Dyneins - metabolism Microtubule-Organizing Center - metabolism Microtubules - genetics Microtubules - metabolism Mitosis - genetics Molecular Sequence Data Protein Kinases - genetics Protein Kinases - metabolism Protein Structure, Tertiary - genetics Protein-Serine-Threonine Kinases Sequence Homology, Amino Acid Spindle Apparatus - genetics Spindle Apparatus - metabolism Xenopus Proteins
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!