Activated Primary and Memory CD8 T Cells Migrate to Nonlymphoid Tissues Regardless of Site of Activation or Tissue of Origin

Following activation within secondary lymphoid tissue, CD8 T cells must migrate to targets, such as infected self tissue, allografts, and tumors, to mediate contact-dependent effector functions. To test whether the pattern of migration of activated CD8 T cells was dependent on the site of Ag encount...

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Veröffentlicht in:	The Journal of immunology (1950) 2004-04, Vol.172 (8), p.4875-4882
Hauptverfasser:	Masopust, David, Vezys, Vaiva, Usherwood, Edward J, Cauley, Linda S, Olson, Sara, Marzo, Amanda L, Ward, Richard L, Woodland, David L, Lefrancois, Leo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adoptive Transfer Animals Bone Marrow Cells - cytology Bone Marrow Cells - immunology Brain - cytology Brain - immunology CD8-Positive T-Lymphocytes - cytology CD8-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - transplantation Cell Movement - genetics Cell Movement - immunology Immunologic Memory - genetics Immunophenotyping Intestinal Mucosa - cytology Intestinal Mucosa - immunology Liver - cytology Liver - immunology Lung - cytology Lung - immunology Lymphocyte Activation - genetics Lymphoid Tissue - cytology Lymphoid Tissue - immunology Mice Mice, Inbred C57BL Mice, Transgenic Organ Specificity - genetics Organ Specificity - immunology Peritoneal Cavity - cytology Respirovirus Infections - immunology Rotavirus Infections - immunology T-Lymphocytes, Regulatory - cytology T-Lymphocytes, Regulatory - immunology
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