Evaluation of the Film-Coating Properties of a Hydroxyethyl Cellulose Hydroxypropyl Methylcellulose Polymer System

ABSTRACT The effect of different grades of hydroxyethyl cellulose (HEC) and hydroxypropyl methylcellulose (HPMC) on the film-formation and taste-masking ability for ibuprofen granules was evaluated. Three batches of coated ibuprofen granules were prepared using a roto-granulator, each with a differe...

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Veröffentlicht in:	Drug development and industrial pharmacy 2002-01, Vol.28 (4), p.389-401
Hauptverfasser:	Li, Shun Por, Martellucci, Stephen A., Bruce, Richard D., Kinyon, Adam C., Hay, Michael B., Higgins, John D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Bones, joints and connective tissue. Antiinflammatory agents Cellulose - analogs & derivatives Cellulose - chemistry Drug Compounding Excipients - chemistry General pharmacology Hydration rate Hypromellose Derivatives Ibuprofen Ibuprofen - chemistry Medical sciences Methylcellulose - analogs & derivatives Methylcellulose - chemistry Microscopy, Electron, Scanning Molecular Weight Molecular weight of polymer Particle Size Pharmaceutical Preparations Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Polymers Solubility Tablets Taste Taste masking Water - chemistry
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