Micellar electrokinetic chromatography for the simultaneous determination of ketorolac tromethamine and its impurities: Multivariate optimization and validation

A simple, fast and selective micellar electrokinetic chromatographic (MEKC) method for the simultaneous assay of ketorolac tromethamine and its known related impurities (1-hydroxy analog of ketorolac, 1-keto analog of ketorolac and decarboxylated ketorolac), in both drug substance and coated tablets...

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Veröffentlicht in:	Journal of Chromatography A 2004-04, Vol.1032 (1), p.253-263
Hauptverfasser:	Orlandini, S., Fanali, S., Furlanetto, S., Marras, A.M., Pinzauti, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Anti-Inflammatory Agents, Non-Steroidal - analysis Biological and medical sciences Calibration Chromatography, Micellar Electrokinetic Capillary - methods Experimental design General pharmacology Ketorolac tromethamine Ketorolac Tromethamine - analysis Medical sciences Multivariate Analysis Nonsteroidal anti-inflammatory drugs Optimization Pharmaceutical analysis Pharmacology. Drug treatments Sensitivity and Specificity Validation
Online-Zugang:	Volltext
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