The Genome-Scale Metabolic Extreme Pathway Structure in Haemophilus influenzae Shows Significant Network Redundancy

Genome-scale metabolic networks can be characterized by a set of systemically independent and unique extreme pathways. These extreme pathways span a convex, high-dimensional space that circumscribes all potential steady-state flux distributions achievable by the defined metabolic network. Genome-sca...

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Veröffentlicht in:Journal of theoretical biology 2002-03, Vol.215 (1), p.67-82
Hauptverfasser: PAPIN, JASON A., PRICE, NATHAN D., EDWARDS, JEREMY S., PALSSON, BERNHARD Ø.
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Sprache:eng
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