Parallel Substrate Binding Sites in a β-Agarase Suggest a Novel Mode of Action on Double-Helical Agarose

Agarose is a gel-forming polysaccharide with an α-L(1,4)-3,6-anhydro-galactose, β-D(1,3)-galactose repeat unit, from the cell walls of marine red algae. β-agarase A, from the Gram-negative bacterium Zobellia galactanivorans, is secreted to the external medium and degrades agarose with an endo-mechan...

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Veröffentlicht in:	Structure (London) 2004-04, Vol.12 (4), p.623-632
Hauptverfasser:	Allouch, Julie, Helbert, William, Henrissat, Bernard, Czjzek, Mirjam
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites Catalytic Domain Crystallization Glycoside Hydrolases - chemistry Glycoside Hydrolases - metabolism Gram-Negative Bacteria - enzymology Gram-Negative Bacteria - metabolism Protein Binding Protein Structure, Tertiary Sepharose - metabolism
Online-Zugang:	Volltext
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