An examination of d-amphetamine self-administration in pedunculopontine tegmental nucleus-lesioned rats

The pedunculopontine tegmental nucleus (PPTg) has long been suggested to have a role in reward-related behaviour, and there is particular interest in its possible role in drug reward systems. Previous work found increased i.v. self-administration (IVSA) of d-amphetamine following PPTg lesions when t...

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Veröffentlicht in:	Neuroscience 2004, Vol.125 (2), p.349-358
Hauptverfasser:	Alderson, H.L, Latimer, M.P, Blaha, C.D, Phillips, A.G, Winn, P
Format:	Artikel
Sprache:	eng
Schlagworte:	acetylcholine Analysis of Variance Animals associative learning Behavior, Animal Biological and medical sciences Central Nervous System Stimulants - administration & dosage Conditioning, Operant - drug effects Dextroamphetamine - administration & dosage dopamine Drug Administration Schedule Excitatory Amino Acid Agonists Food Fundamental and applied biological sciences. Psychology Ibotenic Acid Male mesopontine NADP Pedunculopontine Tegmental Nucleus - drug effects Pedunculopontine Tegmental Nucleus - injuries Pedunculopontine Tegmental Nucleus - physiology Rats Reinforcement (Psychology) Reinforcement Schedule reward Self Administration - methods striatum Vertebrates: nervous system and sense organs
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