Biosynthesis and degradation of anandamide and 2-arachidonoylglycerol and their possible physiological significance

N -arachidonoylethanolamine (anandamide) was the first endogenous cannabinoid receptor ligand to be discovered. Dual synthetic pathways for anandamide have been proposed. One is the formation from free arachidonic acid and ethanolamine, and the other is the formation from N -arachidonoyl phosphatidy...

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Veröffentlicht in:	Prostaglandins, leukotrienes and essential fatty acids leukotrienes and essential fatty acids, 2002-02, Vol.66 (2-3), p.173-192
Hauptverfasser:	Sugiura, T., Kobayashi, Y., Oka, S., Waku, K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arachidonic Acids - analysis Arachidonic Acids - biosynthesis Arachidonic Acids - chemistry Arachidonic Acids - metabolism Endocannabinoids Glycerides - analysis Glycerides - biosynthesis Glycerides - chemistry Glycerides - metabolism Humans Ligands Molecular Structure Organ Specificity Polyunsaturated Alkamides Receptors, Cannabinoid Receptors, Drug - agonists Receptors, Drug - metabolism
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