Iron chelators as therapeutic agents for the treatment of cancer
A wide variety of studies in vitro, in vivo, and in clinical trials have demonstrated that the chelator currently used to treat iron overload disease, desferrioxamine, has anti-proliferative effects against both leukemia and neuroblastoma. However, the efficacy of desferrioxamine is severely limited...
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Veröffentlicht in: | Critical reviews in oncology/hematology 2002-06, Vol.42 (3), p.267-281 |
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