Comparison of Insulin Sensitivity, Clearance, and Secretion Estimates Using Euglycemic and Hyperglycemic Clamps in Children

The euglycemic clamp is the gold standard for estimating insulin sensitivity. The hyperglycemic clamp is easier to perform and is the gold standard for estimating β-cell secretion. Reports in adults suggest that hyperglycemic clamps can estimate insulin sensitivity with results equivalent to euglyce...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2002-06, Vol.87 (6), p.2899-2905
Hauptverfasser:	Uwaifo, G. I., Parikh, S. J., Keil, M., Elberg, J., Chin, J., Yanovski, J. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	African Continental Ancestry Group Beta cells Biological and medical sciences Body composition Body mass index Child Children Cohort Studies Diabetes. Impaired glucose tolerance Dual energy X-ray absorptiometry Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance European Continental Ancestry Group Female Glucose - metabolism Glucose Clamp Technique Humans Hyperglycemia - physiopathology Insulin Insulin - physiology Islets of Langerhans - secretion Magnetic resonance imaging Male Medical sciences Obesity - physiopathology Secretion Thinness
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