Involvement of matrix metalloproteinases in the onset of dentin mineralization

In order to study the involvement of matrix metalloproteinases (MMPs) on dentin formation and mineralization, day 18 embryonic mouse tooth germs were cultured for 10 d in the presence or absence of Marimastat, a general MMP inhibitor, or CT1166, a more selective inhibitor of gelatinases (MMP‐2 and M...

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Veröffentlicht in:	European journal of oral sciences 2004-04, Vol.112 (2), p.171-176
Hauptverfasser:	Fanchon, Stephanie, Bourd, Katia, Septier, Dominique, Everts, Vincent, Beertsen, Wouter, Menashi, Suzanne, Goldberg, Michel
Format:	Artikel
Sprache:	eng
Schlagworte:	Amelogenin Amides - pharmacology Animals Biglycan Culture Techniques Decorin Dental Enamel - drug effects Dental Enamel Proteins - drug effects dentin Dentin - drug effects Dentin - physiology Dentinogenesis - drug effects Dentinogenesis - physiology Dentistry Dose-Response Relationship, Drug Embryo, Mammalian enamel Enzyme Inhibitors - administration & dosage Enzyme Inhibitors - pharmacology Extracellular Matrix Proteins gelatinase Hydroxamic Acids - administration & dosage Hydroxamic Acids - pharmacology Matrix Metalloproteinase 20 Matrix Metalloproteinase Inhibitors Matrix Metalloproteinases - physiology metalloproteinase inhibitors Mice Morpholines - pharmacology Proteoglycans - drug effects stromelysin-1 Tooth Calcification - drug effects Tooth Calcification - physiology Tooth Germ - drug effects Transforming Growth Factor beta - antagonists & inhibitors
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