Interleukin-2-induced Increased Airway Responsiveness and Lung Th2 Cytokine Expression Occur after Antigen Challenge through the Leukotriene Pathway

Previous studies have shown that the allergic late airway response (LR) is dependent on the leukotriene (LT) pathway in Brown Norway (BN) rats. In this same model, interleukin-2 (IL-2) has been shown to increase allergic airway responses without increasing LT production. This study examined the rela...

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Veröffentlicht in:American journal of respiratory and critical care medicine 2002-06, Vol.165 (11), p.1540-1545
Hauptverfasser: Nag, Sammy, Lamkhioued, Bouchaib, Renzi, Paolo M
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Sprache:eng
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