Monitoring mycophenolate in liver transplant recipients: Toward a therapeutic range

Predose plasma mycophenolic acid (MPA) concentrations measured with a semi‐automated enzyme‐multiplied immunoassay were related to adverse events (e.g., rejection, leukopenia, infection), drug dose, and clinical status in 147 adult and 63 pediatric liver allograft recipients receiving adjunctive imm...

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Veröffentlicht in:	Liver transplantation 2004-04, Vol.10 (4), p.492-502
Hauptverfasser:	Tredger, John Michael, Brown, Nigel William, Adams, Jemimah, Gonde, Chris Elton, Dhawan, Anil, Rela, Mohamed, Heaton, Nigel
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Child Child, Preschool Cost-Benefit Analysis Cyclosporine - blood Cyclosporine - therapeutic use Dose-Response Relationship, Drug Drug Monitoring - economics Drug Monitoring - methods Drug Therapy, Combination Female Humans Immunoenzyme Techniques - economics Immunoenzyme Techniques - methods Immunosuppressive Agents - blood Immunosuppressive Agents - therapeutic use Infant Liver Transplantation Male Middle Aged Mycophenolic Acid - analogs & derivatives Mycophenolic Acid - blood Mycophenolic Acid - therapeutic use Tacrolimus - blood Tacrolimus - therapeutic use Transplantation
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