Tonin expression in the rat brain and tonin-mediated central production of angiotensin II

Tonins are serine proteinases mainly found in the rat submandibular gland, which are capable of generating the pressor octapeptide angiotensin II (Ang II) not only from the classical substrate angiotensin I but also from the synthetic tetradecapeptide (AG(1–14)) and from angiotensinogen. In this wor...

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Veröffentlicht in:	Physiology & behavior 2002-06, Vol.76 (2), p.327-333
Hauptverfasser:	Araujo, Ronaldo C, Lima, Mercia P, Lomez, Eliane S.L, Bader, Michael, Pesquero, Joao B, Sumitani, Marie, Pesquero, Jorge L
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - biosynthesis Angiotensin II - biosynthesis Animals Astrocytes - metabolism Biochemistry and metabolism Biological and medical sciences Blood pressure Blood Pressure - drug effects Blood Pressure - physiology Brain Chemistry - drug effects Brain Chemistry - physiology Central nervous system Drinking Drinking Behavior - drug effects Fundamental and applied biological sciences. Psychology Injections, Intraventricular Mesencephalon - cytology Mesencephalon - drug effects Mesencephalon - metabolism Nervous system Nuclease Protection Assays Rats Rats, Wistar Reverse Transcriptase Polymerase Chain Reaction Saline intake Serine Endopeptidases - biosynthesis Serine Endopeptidases - pharmacology Tissue Kallikreins - biosynthesis Tissue Kallikreins - pharmacology Tonin expression Urodynamics - drug effects Vertebrates: nervous system and sense organs
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