Melatonin alleviates jet lag symptoms caused by an 11‐hour eastward flight
The effect of 3 mg of melatonin on the rate of re‐entrainment of plasma melatonin rhythm after an 11‐h eastward flight was assessed. Eight subjects participated in the study, and underwent 24‐h blood samplings once before the flight and twice after the flight. Subjects were exposed to natural zeitge...
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| Veröffentlicht in: | Psychiatry and clinical neurosciences 2002-06, Vol.56 (3), p.301-302 |
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| creator | TAKAHASHI, TOSHIHARU SASAKI, MITSUO ITOH, HIROSHI YAMADERA, WATARU OZONE, MOTOHIRO OBUCHI, KEITA HAYASHIDA, KEN‐ICHI MATSUNAGA, NAOKI SANO, HIDETAKA |
| description | The effect of 3 mg of melatonin on the rate of re‐entrainment of plasma melatonin rhythm after an 11‐h eastward flight was assessed. Eight subjects participated in the study, and underwent 24‐h blood samplings once before the flight and twice after the flight. Subjects were exposed to natural zeitgeber outdoors and took 3 mg of malatonin at 20:00 h local time on the days when no blood sampling was done. Antidromic re‐entrainment was dominant whereby melatonin administration in the evening promoted re‐entrainment. Melatonin accelerated the rate of re‐entrainment by 15 min per day and alleviated the jet lag symptoms. |
| doi_str_mv | 10.1046/j.1440-1819.2002.00988.x |
| format | Article |
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Eight subjects participated in the study, and underwent 24‐h blood samplings once before the flight and twice after the flight. Subjects were exposed to natural zeitgeber outdoors and took 3 mg of malatonin at 20:00 h local time on the days when no blood sampling was done. Antidromic re‐entrainment was dominant whereby melatonin administration in the evening promoted re‐entrainment. Melatonin accelerated the rate of re‐entrainment by 15 min per day and alleviated the jet lag symptoms.</description><subject>Adult</subject><subject>antidromic re‐entrainment</subject><subject>Aviation</subject><subject>eastward flight</subject><subject>Humans</subject><subject>Japan</subject><subject>Jet lag</subject><subject>Jet Lag Syndrome - drug therapy</subject><subject>Male</subject><subject>Melatonin</subject><subject>Melatonin - therapeutic use</subject><subject>Middle Aged</subject><subject>natural zeitgeber</subject><subject>New York</subject><subject>orthodromic re‐entrainment</subject><subject>Time Factors</subject><subject>Treatment</subject><issn>1323-1316</issn><issn>1440-1819</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><recordid>eNqNkE1OwzAQhS0EoqVwBeQVu4QZ20kciQ2q-JPKzwLWlpM4bSqnKXFC2x1H4IychIRWsITVjDTvvXn6CKEIPoIIz-c-CgEeSox9BsB8gFhKf71Hhj-H_W7njHvIMRyQI-fmAMB5iIdkgAxEFEIwJJN7Y3VTLYoF1daat0I3xtG5aajVU-o25bKpSkdT3TqT0WRD9YIifr5_zKq2pka7ZqXrjOa2mM6aY3KQa-vMyW6OyMv11fP41ps83tyNLydeGqCQHosF6BgYl1kcCWOkFgh5kHWtEx6mkAELsijMGEOdB5iINEwSZEkcY5ByyfmInG1zl3X12hrXqLJwqbFWL0zVOhVhJAWg-FMYRJJ3PfpEuRWmdeVcbXK1rItS1xuFoHrkaq56sqonq3rk6hu5WnfW092PNilN9mvcMe4EF1vBqrBm8-9g9TR-6Bb-Bfp1jpk</recordid><startdate>200206</startdate><enddate>200206</enddate><creator>TAKAHASHI, TOSHIHARU</creator><creator>SASAKI, MITSUO</creator><creator>ITOH, HIROSHI</creator><creator>YAMADERA, WATARU</creator><creator>OZONE, MOTOHIRO</creator><creator>OBUCHI, KEITA</creator><creator>HAYASHIDA, KEN‐ICHI</creator><creator>MATSUNAGA, NAOKI</creator><creator>SANO, HIDETAKA</creator><general>Blackwell Science Pty</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QJ</scope><scope>7X8</scope></search><sort><creationdate>200206</creationdate><title>Melatonin alleviates jet lag symptoms caused by an 11‐hour eastward flight</title><author>TAKAHASHI, TOSHIHARU ; SASAKI, MITSUO ; ITOH, HIROSHI ; YAMADERA, WATARU ; OZONE, MOTOHIRO ; OBUCHI, KEITA ; HAYASHIDA, KEN‐ICHI ; MATSUNAGA, NAOKI ; SANO, HIDETAKA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5148-2940a90238d974ee8a410f5d181b36c0d025d76d221af51b4c6bb12b9915c3833</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Adult</topic><topic>antidromic re‐entrainment</topic><topic>Aviation</topic><topic>eastward flight</topic><topic>Humans</topic><topic>Japan</topic><topic>Jet lag</topic><topic>Jet Lag Syndrome - drug therapy</topic><topic>Male</topic><topic>Melatonin</topic><topic>Melatonin - therapeutic use</topic><topic>Middle Aged</topic><topic>natural zeitgeber</topic><topic>New York</topic><topic>orthodromic re‐entrainment</topic><topic>Time Factors</topic><topic>Treatment</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>TAKAHASHI, TOSHIHARU</creatorcontrib><creatorcontrib>SASAKI, MITSUO</creatorcontrib><creatorcontrib>ITOH, HIROSHI</creatorcontrib><creatorcontrib>YAMADERA, WATARU</creatorcontrib><creatorcontrib>OZONE, MOTOHIRO</creatorcontrib><creatorcontrib>OBUCHI, KEITA</creatorcontrib><creatorcontrib>HAYASHIDA, KEN‐ICHI</creatorcontrib><creatorcontrib>MATSUNAGA, NAOKI</creatorcontrib><creatorcontrib>SANO, HIDETAKA</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>MEDLINE - Academic</collection><jtitle>Psychiatry and clinical neurosciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>TAKAHASHI, TOSHIHARU</au><au>SASAKI, MITSUO</au><au>ITOH, HIROSHI</au><au>YAMADERA, WATARU</au><au>OZONE, MOTOHIRO</au><au>OBUCHI, KEITA</au><au>HAYASHIDA, KEN‐ICHI</au><au>MATSUNAGA, NAOKI</au><au>SANO, HIDETAKA</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Melatonin alleviates jet lag symptoms caused by an 11‐hour eastward flight</atitle><jtitle>Psychiatry and clinical neurosciences</jtitle><addtitle>Psychiatry Clin Neurosci</addtitle><date>2002-06</date><risdate>2002</risdate><volume>56</volume><issue>3</issue><spage>301</spage><epage>302</epage><pages>301-302</pages><issn>1323-1316</issn><eissn>1440-1819</eissn><abstract>The effect of 3 mg of melatonin on the rate of re‐entrainment of plasma melatonin rhythm after an 11‐h eastward flight was assessed. Eight subjects participated in the study, and underwent 24‐h blood samplings once before the flight and twice after the flight. Subjects were exposed to natural zeitgeber outdoors and took 3 mg of malatonin at 20:00 h local time on the days when no blood sampling was done. Antidromic re‐entrainment was dominant whereby melatonin administration in the evening promoted re‐entrainment. Melatonin accelerated the rate of re‐entrainment by 15 min per day and alleviated the jet lag symptoms.</abstract><cop>Melbourne, Australia</cop><pub>Blackwell Science Pty</pub><pmid>12047605</pmid><doi>10.1046/j.1440-1819.2002.00988.x</doi><tpages>2</tpages></addata></record> |
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| source | Applied Social Sciences Index & Abstracts (ASSIA); Wiley Online Library - AutoHoldings Journals; MEDLINE; Freely Accessible Japanese Titles; Wiley Online Library Free Content; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Adult antidromic re‐entrainment Aviation eastward flight Humans Japan Jet lag Jet Lag Syndrome - drug therapy Male Melatonin Melatonin - therapeutic use Middle Aged natural zeitgeber New York orthodromic re‐entrainment Time Factors Treatment |
| title | Melatonin alleviates jet lag symptoms caused by an 11‐hour eastward flight |
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