Renal excretion of 8-oxo-7,8-dihydro-2 ′-deoxyguanosine: degradation rates of RNA and metabolic rate in humans

Renally excreted 8-oxo-7,8-dihydro-2 ′-deoxyguanosine (oxo 8dG) is a potential marker of oxidative DNA damage by reactive oxygen species. Whole-body degradation rates of t- and rRNA are potential indicators of the resting metabolic rate (RMR). Excretion rates of oxo 8dG and degradation rates of t- a...

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Veröffentlicht in:	Archives of biochemistry and biophysics 2002-06, Vol.402 (1), p.31-37
Hauptverfasser:	Topp, Heinrich, Armbrust, Sven, Lengger, Christoph, Schöch, Gerhard, Davies, Joanne, Stichler, Willibald, Manz, Friedrich, Fusch, Christoph
Format:	Artikel
Sprache:	eng
Schlagworte:	8-Oxo-7,8-dihydro-2 ′-deoxyguanosine Absorptiometry, Photon Adult Basal Metabolism - physiology Calorimetry, Indirect Child Densitometry Deoxyguanosine - analogs & derivatives Deoxyguanosine - metabolism DNA DNA Damage Energy metabolism Energy Metabolism - physiology Female Humans Kidney - metabolism Male Modified ribonucleosides Oxidative Stress Reactive oxygen species Reactive Oxygen Species - metabolism RNA RNA, Ribosomal - metabolism RNA, Transfer - metabolism
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