Tight glycemic control in diabetic coronary artery bypass graft patients improves perioperative outcomes and decreases recurrent ischemic events

This study sought to determine whether tight glycemic control with a modified glucose-insulin-potassium (GIK) solution in diabetic coronary artery bypass graft (CABG) patients would improve perioperative outcomes. One hundred forty-one diabetic patients undergoing CABG were prospectively randomized...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2004-03, Vol.109 (12), p.1497-1502
Hauptverfasser:	LAZAR, Harold L, CHIPKIN, Stuart R, FITZGERALD, Carmel A, YUSHENG BAO, CABRAL, Howard, APSTEIN, Carl S
Format:	Artikel
Sprache:	eng
Schlagworte:	Atrial Fibrillation - prevention & control Biological and medical sciences Blood and lymphatic vessels Blood Glucose - analysis Cardiology. Vascular system Cardioplegic Solutions - administration & dosage Cardioplegic Solutions - therapeutic use Cardiotonic Agents - administration & dosage Cardiotonic Agents - therapeutic use Coronary Artery Bypass Coronary Stenosis - complications Coronary Stenosis - surgery Diabetes Complications Diabetes Mellitus - blood Diabetes Mellitus - drug therapy Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Fatty Acids, Nonesterified - blood Female Glucose - administration & dosage Glucose - therapeutic use Humans Insulin - administration & dosage Insulin - therapeutic use Lactates - blood Length of Stay - statistics & numerical data Male Medical sciences Middle Aged Postoperative Complications - prevention & control Potassium - administration & dosage Potassium - therapeutic use Recurrence Surgical Wound Infection - epidemiology Treatment Outcome
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Beschreibung
Zusammenfassung:	This study sought to determine whether tight glycemic control with a modified glucose-insulin-potassium (GIK) solution in diabetic coronary artery bypass graft (CABG) patients would improve perioperative outcomes. One hundred forty-one diabetic patients undergoing CABG were prospectively randomized to tight glycemic control (serum glucose, 125 to 200 mg/dL) with GIK or standard therapy (serum glucose
ISSN:	0009-7322 1524-4539
DOI:	10.1161/01.CIR.0000121747.71054.79