Palmitate increases nitric oxide synthase activity that is involved in palmitate-induced cell death in cardiomyocytes

The objective of this study was to test the hypothesis that nitric oxide synthase (NOS) is subjected to regulatory control by palmitate, and that nitric oxide (NO) is operative in palmitate-induced cell death. Palmitate induced a significant ( p

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Bibliographische Detailangaben
Veröffentlicht in:	Nitric oxide 2004-02, Vol.10 (1), p.11-19
Hauptverfasser:	Tsang, Michael Y.C., Cowie, Scott E., Rabkin, Simon W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell death Cell Death - drug effects Chick Embryo eNOS Greiss reaction Heart iNOS Myocytes, Cardiac - cytology Myocytes, Cardiac - enzymology NG-Nitroarginine Methyl Ester - pharmacology Nitric Oxide - pharmacology Nitric oxide synthase Nitric Oxide Synthase - analysis Nitric Oxide Synthase - drug effects Nitric Oxide Synthase - metabolism Nitric Oxide Synthase Type II Nitric Oxide Synthase Type III Palmitate Palmitic Acid - pharmacology
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Beschreibung
Zusammenfassung:	The objective of this study was to test the hypothesis that nitric oxide synthase (NOS) is subjected to regulatory control by palmitate, and that nitric oxide (NO) is operative in palmitate-induced cell death. Palmitate induced a significant ( p
ISSN:	1089-8603 1089-8611
DOI:	10.1016/j.niox.2004.01.005