Effects of trypsin on large-conductance Ca(2+)-activated K(+) channels of guinea-pig outer hair cells

High-conductance Ca(2+)-activated K(+) (BK(Ca)) channels from isolated adult guinea-pig outer hair cells were studied in inside-out membrane patches. They had a 300 pS unitary conductance and were inhibited by tetraethyl ammonium (1 mM), iberiotoxin (33 nM) and charybdotoxin (50 nM). In symmetrical...

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Veröffentlicht in:Hearing research 2004-04, Vol.190 (1-2), p.115-127
Hauptverfasser: Spreadbury, I C, Kros, C J, Meech, R W
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Sprache:eng
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