Antitumor activity of the polyamine analog N', N-diethylnorspermine against human prostate carcinoma cells

Recent studies indicate that N-terminally bis-ethylated-polyamine analogs have significant antitumor activity in several human solid-tumor models. In this study, the in vitro and in vivo antitumor potential of the polyamine analog N(1), N(11)-diethylnorspermine (DENSpm) in human prostate carcinoma c...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Prostate 2000-09, Vol.44 (4), p.313-321
Hauptverfasser:	SCHIPPER, R. G, DELI, G, DELOYER, P, LANGE, W. P. H. J, SCHALKEN, J. A, VERHOFSTAD, A. A. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetyltransferases - biosynthesis Acetyltransferases - metabolism Animals Antineoplastic Agents - metabolism Antineoplastic Agents - pharmacology Biogenic Polyamines - metabolism Biological and medical sciences Carcinoma - drug therapy Carcinoma - enzymology Carcinoma - pathology Cell Division - drug effects Drug Screening Assays, Antitumor Enzyme Induction - drug effects Female Humans Male Medical sciences Mice Mice, Inbred BALB C Mice, Nude Neoplasm Transplantation Ornithine Decarboxylase - metabolism Ornithine Decarboxylase Inhibitors Pharmacology. Drug treatments Prostatic Neoplasms - drug therapy Prostatic Neoplasms - enzymology Prostatic Neoplasms - pathology Spermine - analogs & derivatives Spermine - metabolism Spermine - pharmacology Transplantation, Heterologous Tumor Cells, Cultured Urinary system
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!