Proliferating Cell Nuclear Antigen Associates with Histone Deacetylase Activity, Integrating DNA Replication and Chromatin Modification

Faithful inheritance of the chromatin structure is essential for maintaining the gene expression integrity of a cell. Histone modification by acetylation and deacetylation is a critical control of chromatin structure. In this study, we test the hypothesis that histone deacetylase 1 (HDAC1) is physic...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The Journal of biological chemistry 2002-06, Vol.277 (23), p.20974-20978
Hauptverfasser:	Milutinovic, Snezana, Zhuang, Qianli, Szyf, Moshe
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Cycle - drug effects Chromatin - metabolism DNA Replication epigenetics Flow Cytometry Histone Deacetylases - metabolism Humans Hydroxamic Acids - pharmacology Proliferating Cell Nuclear Antigen - metabolism Protein Binding trichostatin A Tumor Cells, Cultured
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!