Dual-mesh optical tomography reconstruction method with a depth correction that uses a priori ultrasound information
A dual-mesh reconstruction method with a depth correction for near-infrared diffused wave imaging with ultrasound localization is demonstrated by use of phantoms and clinical cancer cases. Column normalization is applied to the weight matrix obtained from the Born approximation to correct the depth-...
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| Veröffentlicht in: | Applied optics (2004) 2004-03, Vol.43 (8), p.1654-1662 |
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| container_title | Applied optics (2004) |
| container_volume | 43 |
| creator | Huang, Minming Zhu, Quing |
| description | A dual-mesh reconstruction method with a depth correction for near-infrared diffused wave imaging with ultrasound localization is demonstrated by use of phantoms and clinical cancer cases. Column normalization is applied to the weight matrix obtained from the Born approximation to correct the depth-dependent problem in the reconstructed absorption maps as well as in the total hemoglobin concentration maps. With the depth correction, more uniform absorption maps for target layers at different depths are obtained from the phantoms, and the correlation between the reconstructed hemoglobin concentration maps of deeply located, large cancers and the histological microvessel density counts are dramatically improved. |
| doi_str_mv | 10.1364/AO.43.001654 |
| format | Article |
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Column normalization is applied to the weight matrix obtained from the Born approximation to correct the depth-dependent problem in the reconstructed absorption maps as well as in the total hemoglobin concentration maps. With the depth correction, more uniform absorption maps for target layers at different depths are obtained from the phantoms, and the correlation between the reconstructed hemoglobin concentration maps of deeply located, large cancers and the histological microvessel density counts are dramatically improved.</description><identifier>ISSN: 1559-128X</identifier><identifier>DOI: 10.1364/AO.43.001654</identifier><identifier>PMID: 15046168</identifier><language>eng</language><publisher>United States</publisher><subject>Adult ; Breast Neoplasms - diagnosis ; Carcinoma, Intraductal, Noninfiltrating - diagnosis ; Female ; Humans ; Image Processing, Computer-Assisted - methods ; Middle Aged ; Models, Theoretical ; Neoplasm Invasiveness - diagnosis ; Phantoms, Imaging ; Pregnancy ; Pregnancy Complications, Neoplastic - diagnosis ; Scattering, Radiation ; Spectroscopy, Near-Infrared ; Tomography, Optical ; Ultrasonography</subject><ispartof>Applied optics (2004), 2004-03, Vol.43 (8), p.1654-1662</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15046168$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Huang, Minming</creatorcontrib><creatorcontrib>Zhu, Quing</creatorcontrib><title>Dual-mesh optical tomography reconstruction method with a depth correction that uses a priori ultrasound information</title><title>Applied optics (2004)</title><addtitle>Appl Opt</addtitle><description>A dual-mesh reconstruction method with a depth correction for near-infrared diffused wave imaging with ultrasound localization is demonstrated by use of phantoms and clinical cancer cases. Column normalization is applied to the weight matrix obtained from the Born approximation to correct the depth-dependent problem in the reconstructed absorption maps as well as in the total hemoglobin concentration maps. 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| fulltext | fulltext |
| identifier | ISSN: 1559-128X |
| ispartof | Applied optics (2004), 2004-03, Vol.43 (8), p.1654-1662 |
| issn | 1559-128X |
| language | eng |
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| source | MEDLINE; Optica Publishing Group Journals |
| subjects | Adult Breast Neoplasms - diagnosis Carcinoma, Intraductal, Noninfiltrating - diagnosis Female Humans Image Processing, Computer-Assisted - methods Middle Aged Models, Theoretical Neoplasm Invasiveness - diagnosis Phantoms, Imaging Pregnancy Pregnancy Complications, Neoplastic - diagnosis Scattering, Radiation Spectroscopy, Near-Infrared Tomography, Optical Ultrasonography |
| title | Dual-mesh optical tomography reconstruction method with a depth correction that uses a priori ultrasound information |
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