Transforming growth factor-beta 1 production is correlated with genetically determined ACE expression in congenic rats: a possible link between ACE genotype and diabetic nephropathy

Genetic background appears to modulate the development of diabetic vascular complications. In particular, polymorphisms in the ACE gene have been associated with diabetic nephropathy and, in some studies, macrovascular complications. However, the links between ACE gene polymorphism and factors impli...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2004-04, Vol.53 (4), p.1111-1118
Hauptverfasser:	Pueyo, Maria E, Challah, Mireille, Gauguier, Dominique, Louedec, Liliane, Philippe, Monique, Gaertner, Roger, Marre, Michel, Michel, Jean-Baptiste, Jacob, Marie-Paule
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Pressure Chromosome Mapping Crosses, Genetic Diabetic Angiopathies - genetics Diabetic Nephropathies - genetics Gene Expression Regulation, Enzymologic - genetics Genetic Markers Genotype Heart Rate Peptidyl-Dipeptidase A - genetics Rats Rats, Inbred BN Rats, Mutant Strains Renin - blood RNA, Messenger - genetics Transcription, Genetic - genetics Transforming Growth Factor beta - blood Transforming Growth Factor beta - genetics
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