An algebraic model of RNA duplex formation
We propose a simple algebraic description of the two‐body interactions of bases in RNA thermodynamics showing in detail qualitative equivalence with conventional nearest‐neighbor models. The process of obtaining base content, polymer, and oligomer parameters is illustrated, and for duplexes containi...
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Veröffentlicht in: | Biopolymers 2004-04, Vol.73 (6), p.657-667 |
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description | We propose a simple algebraic description of the two‐body interactions of bases in RNA thermodynamics showing in detail qualitative equivalence with conventional nearest‐neighbor models. The process of obtaining base content, polymer, and oligomer parameters is illustrated, and for duplexes containing Watson–Crick pairs, fits to oligonucleotide duplex heat‐of‐formation data are shown to be statistically equivalent to existing models. © 2004 Wiley Periodicals, Inc. Biopolymers, 2004 |
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Biopolymers, 2004</description><subject>Base Pairing</subject><subject>Hydrogen Bonding</subject><subject>Models, Chemical</subject><subject>nearest neighbor properties</subject><subject>Nucleic Acid Conformation</subject><subject>Nucleic Acid Heteroduplexes - chemistry</subject><subject>RNA - chemistry</subject><subject>RNA secondary structure</subject><subject>Thermodynamics</subject><issn>0006-3525</issn><issn>1097-0282</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM1Kw0AYRQdRbK0ufAHJSlBIOz-Zv2UtWgtStSguh5nJRKJJE2cabN_eaKquxNV3F-eeDy4AxwgOEYR4ZPJ6iNuAd0AfQcljiAXeBX0IIYsJxbQHDkJ4gTBJCIL7oIcoTARnsg_Ox8tIF8_OeJ3bqKxSV0RVFi3m4yht6sKto6zypV7l1fIQ7GW6CO5oewfg8eryYXId39xOZ5PxTWyJhDhGxKVIZolEjEkijSUGCW64pZk1nCBuLEtTSYgQ2lnBsEghJprZjBLZZjIAp5239tVb48JKlXmwrij00lVNUBxxhhNK_gURb79QiVvwrAOtr0LwLlO1z0vtNwpB9bmgahdUXwu27MlW2pjSpb_kdrIWGHXAe164zd8mdTG7-1bGXSMPK7f-aWj_qhgnnKqn-VTReyYniylRgnwAa5CGUw</recordid><startdate>20040415</startdate><enddate>20040415</enddate><creator>Bashford, J. 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subjects | Base Pairing Hydrogen Bonding Models, Chemical nearest neighbor properties Nucleic Acid Conformation Nucleic Acid Heteroduplexes - chemistry RNA - chemistry RNA secondary structure Thermodynamics |
title | An algebraic model of RNA duplex formation |
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