Contractile cardiac grafts using a novel nanofibrous mesh

Cardiomyoctes are terminally differentiated cells and therefore unable to regenerate after infarction. The use of autologous bioengineered cardiac grafts has been suggested to replace infarcted myocardium and enhance cardiac function. Here we report the development of an in vitro system for engineer...

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Veröffentlicht in:	Biomaterials 2004-08, Vol.25 (17), p.3717-3723
Hauptverfasser:	Shin, M., Ishii, O., Sueda, T., Vacanti, J.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Biocompatible Materials - chemistry Cardiac tissue engineering Cell Adhesion - physiology Cell Division - physiology Cell Survival - physiology Cells, Cultured Electrochemistry - methods Electrospinning Heart Materials Testing Membranes, Artificial Myocytes, Cardiac - cytology Myocytes, Cardiac - physiology Nanotechnology - methods Nanotubes - chemistry Nanotubes - ultrastructure Polycaprolactone Polyesters - chemistry Porosity Rats Rats, Inbred Lew Textiles Tissue Engineering - methods
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