Pilot study of combined blockade of the renin–angiotensin system in essential hypertensive patients

BACKGROUNDAdditive hemodynamic effects of combined blockade of the renin–angiotensin system by an angiotensin I converting enzyme inhibitor and an angiotensin II antagonist have been observed in sodium-depleted normotensive volunteers and in patients with congestive heart failure. OBJECTIVETo invest...

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Veröffentlicht in:	Journal of hypertension 2000-08, Vol.18 (8), p.1139-1147
Hauptverfasser:	Azizi, Michel, Linhart, Ales, Alexander, Joe, Goldberg, Allan, Menten, Joris, Sweet, Charles, Ménard, Joël
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Angiotensin II - antagonists & inhibitors Angiotensin-Converting Enzyme Inhibitors - therapeutic use Antihypertensive agents Antihypertensive Agents - therapeutic use Biological and medical sciences Biomarkers Blood Pressure - drug effects Cardiovascular system Double-Blind Method Drug Therapy, Combination Enalapril - therapeutic use Female Humans Hypertension - drug therapy Hypertension - physiopathology Losartan - therapeutic use Male Medical sciences Middle Aged Pharmacology. Drug treatments Pilot Projects Renin-Angiotensin System - drug effects Treatment Outcome
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