Videoendoscopic Thoracic Aorta-to-Femoral Artery Bypass in the Pig

Background. The thoracoscopic approach to the aorta has the advantages of easy aortic dissection, excellent inflow, improved exposure in the thorax without insufflation, and ability to employ both laparoscopic and traditional instruments. Our aim was to develop a thoracoscopic technique for descendi...

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Veröffentlicht in:The Journal of surgical research 2000-09, Vol.93 (1), p.70-74
Hauptverfasser: Noel, Audra A., Gloviczki, Peter, Young, Mary M., Karnicki, Krzysztof, Deschamps, Claude, Moir, Christopher
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container_end_page 74
container_issue 1
container_start_page 70
container_title The Journal of surgical research
container_volume 93
creator Noel, Audra A.
Gloviczki, Peter
Young, Mary M.
Karnicki, Krzysztof
Deschamps, Claude
Moir, Christopher
description Background. The thoracoscopic approach to the aorta has the advantages of easy aortic dissection, excellent inflow, improved exposure in the thorax without insufflation, and ability to employ both laparoscopic and traditional instruments. Our aim was to develop a thoracoscopic technique for descending thoracic aorta-to-femoral artery bypass (TAFB) in the pig that results in acceptable short-term survival and graft patency. Materials and methods. Thoracoscopic TAFB was performed in 11 pigs. Using two-lung ventilation, the animals were placed in a 45° left lateral semidecubitus position. A fan lung retractor, two dissecting ports, intercostal artery loops, and camera were placed through five 10- to 20-mm thoracoscopic incisions. After aortic dissection, an 8-mm graft was passed through a retroperitoneal tunnel. Rumel tourniquets were used for aortic occlusion after placement of a shunt. End-to-side endoscopic anastomosis was completed with knots tied extracorporeally. The left femoral anastomosis was completed under direct vision. Duplex ultrasound of the graft was done on postoperative days 1, 3, and 7. Results. Thoracoscopic TAFB was completed in all animals. Mean aortic anastomosis time was 57 min (range, 34–145); and mean cross-clamp time, 74 min (range, 53–155). Mean operative time was 310 min; the first six operations lasted longer than the last five (338 min vs 276 min, P < 0.04). Average blood loss was 611 ml (range, 250–1300). Two animals died due to anesthetic complications. One (11%) of the nine surviving pigs died on day 2 due to bleeding. Complications were paraplegia in one (11%) and graft thrombosis in another (11%). Conclusions. Videoendoscopic TAFB can be completed in pigs with acceptable short-term patency and survival. Further experience in thoracoscopic techniques can make TAFB a feasible and low-risk option for selected patients with aortoiliac occlusive disease.
doi_str_mv 10.1006/jsre.2000.5933
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The thoracoscopic approach to the aorta has the advantages of easy aortic dissection, excellent inflow, improved exposure in the thorax without insufflation, and ability to employ both laparoscopic and traditional instruments. Our aim was to develop a thoracoscopic technique for descending thoracic aorta-to-femoral artery bypass (TAFB) in the pig that results in acceptable short-term survival and graft patency. Materials and methods. Thoracoscopic TAFB was performed in 11 pigs. Using two-lung ventilation, the animals were placed in a 45° left lateral semidecubitus position. A fan lung retractor, two dissecting ports, intercostal artery loops, and camera were placed through five 10- to 20-mm thoracoscopic incisions. After aortic dissection, an 8-mm graft was passed through a retroperitoneal tunnel. Rumel tourniquets were used for aortic occlusion after placement of a shunt. End-to-side endoscopic anastomosis was completed with knots tied extracorporeally. The left femoral anastomosis was completed under direct vision. Duplex ultrasound of the graft was done on postoperative days 1, 3, and 7. Results. Thoracoscopic TAFB was completed in all animals. Mean aortic anastomosis time was 57 min (range, 34–145); and mean cross-clamp time, 74 min (range, 53–155). Mean operative time was 310 min; the first six operations lasted longer than the last five (338 min vs 276 min, P &lt; 0.04). Average blood loss was 611 ml (range, 250–1300). Two animals died due to anesthetic complications. One (11%) of the nine surviving pigs died on day 2 due to bleeding. Complications were paraplegia in one (11%) and graft thrombosis in another (11%). Conclusions. Videoendoscopic TAFB can be completed in pigs with acceptable short-term patency and survival. Further experience in thoracoscopic techniques can make TAFB a feasible and low-risk option for selected patients with aortoiliac occlusive disease.</description><identifier>ISSN: 0022-4804</identifier><identifier>EISSN: 1095-8673</identifier><identifier>DOI: 10.1006/jsre.2000.5933</identifier><identifier>PMID: 10945945</identifier><identifier>CODEN: JSGRA2</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Anastomosis, Surgical ; Animals ; aorta ; Aorta, Thoracic - surgery ; Biological and medical sciences ; bypass ; Femoral Artery - surgery ; laparoscopic ; Medical sciences ; Postoperative Complications ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Swine ; Thoracoscopy ; Vascular surgery: aorta, extremities, vena cava. 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The thoracoscopic approach to the aorta has the advantages of easy aortic dissection, excellent inflow, improved exposure in the thorax without insufflation, and ability to employ both laparoscopic and traditional instruments. Our aim was to develop a thoracoscopic technique for descending thoracic aorta-to-femoral artery bypass (TAFB) in the pig that results in acceptable short-term survival and graft patency. Materials and methods. Thoracoscopic TAFB was performed in 11 pigs. Using two-lung ventilation, the animals were placed in a 45° left lateral semidecubitus position. A fan lung retractor, two dissecting ports, intercostal artery loops, and camera were placed through five 10- to 20-mm thoracoscopic incisions. After aortic dissection, an 8-mm graft was passed through a retroperitoneal tunnel. Rumel tourniquets were used for aortic occlusion after placement of a shunt. End-to-side endoscopic anastomosis was completed with knots tied extracorporeally. The left femoral anastomosis was completed under direct vision. Duplex ultrasound of the graft was done on postoperative days 1, 3, and 7. Results. Thoracoscopic TAFB was completed in all animals. Mean aortic anastomosis time was 57 min (range, 34–145); and mean cross-clamp time, 74 min (range, 53–155). Mean operative time was 310 min; the first six operations lasted longer than the last five (338 min vs 276 min, P &lt; 0.04). Average blood loss was 611 ml (range, 250–1300). Two animals died due to anesthetic complications. One (11%) of the nine surviving pigs died on day 2 due to bleeding. Complications were paraplegia in one (11%) and graft thrombosis in another (11%). Conclusions. Videoendoscopic TAFB can be completed in pigs with acceptable short-term patency and survival. 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Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Swine</topic><topic>Thoracoscopy</topic><topic>Vascular surgery: aorta, extremities, vena cava. Surgery of the lymphatic vessels</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Noel, Audra A.</creatorcontrib><creatorcontrib>Gloviczki, Peter</creatorcontrib><creatorcontrib>Young, Mary M.</creatorcontrib><creatorcontrib>Karnicki, Krzysztof</creatorcontrib><creatorcontrib>Deschamps, Claude</creatorcontrib><creatorcontrib>Moir, Christopher</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of surgical research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Noel, Audra A.</au><au>Gloviczki, Peter</au><au>Young, Mary M.</au><au>Karnicki, Krzysztof</au><au>Deschamps, Claude</au><au>Moir, Christopher</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Videoendoscopic Thoracic Aorta-to-Femoral Artery Bypass in the Pig</atitle><jtitle>The Journal of surgical research</jtitle><addtitle>J Surg Res</addtitle><date>2000-09-01</date><risdate>2000</risdate><volume>93</volume><issue>1</issue><spage>70</spage><epage>74</epage><pages>70-74</pages><issn>0022-4804</issn><eissn>1095-8673</eissn><coden>JSGRA2</coden><abstract>Background. The thoracoscopic approach to the aorta has the advantages of easy aortic dissection, excellent inflow, improved exposure in the thorax without insufflation, and ability to employ both laparoscopic and traditional instruments. Our aim was to develop a thoracoscopic technique for descending thoracic aorta-to-femoral artery bypass (TAFB) in the pig that results in acceptable short-term survival and graft patency. Materials and methods. Thoracoscopic TAFB was performed in 11 pigs. Using two-lung ventilation, the animals were placed in a 45° left lateral semidecubitus position. A fan lung retractor, two dissecting ports, intercostal artery loops, and camera were placed through five 10- to 20-mm thoracoscopic incisions. After aortic dissection, an 8-mm graft was passed through a retroperitoneal tunnel. Rumel tourniquets were used for aortic occlusion after placement of a shunt. End-to-side endoscopic anastomosis was completed with knots tied extracorporeally. The left femoral anastomosis was completed under direct vision. Duplex ultrasound of the graft was done on postoperative days 1, 3, and 7. Results. Thoracoscopic TAFB was completed in all animals. Mean aortic anastomosis time was 57 min (range, 34–145); and mean cross-clamp time, 74 min (range, 53–155). Mean operative time was 310 min; the first six operations lasted longer than the last five (338 min vs 276 min, P &lt; 0.04). Average blood loss was 611 ml (range, 250–1300). Two animals died due to anesthetic complications. One (11%) of the nine surviving pigs died on day 2 due to bleeding. Complications were paraplegia in one (11%) and graft thrombosis in another (11%). Conclusions. Videoendoscopic TAFB can be completed in pigs with acceptable short-term patency and survival. Further experience in thoracoscopic techniques can make TAFB a feasible and low-risk option for selected patients with aortoiliac occlusive disease.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>10945945</pmid><doi>10.1006/jsre.2000.5933</doi><tpages>5</tpages></addata></record>
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subjects Anastomosis, Surgical
Animals
aorta
Aorta, Thoracic - surgery
Biological and medical sciences
bypass
Femoral Artery - surgery
laparoscopic
Medical sciences
Postoperative Complications
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Swine
Thoracoscopy
Vascular surgery: aorta, extremities, vena cava. Surgery of the lymphatic vessels
title Videoendoscopic Thoracic Aorta-to-Femoral Artery Bypass in the Pig
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