Single-Cell Analysis by a Scanning Thermal Lens Microscope with a Microchip: Direct Monitoring of Cytochrome c Distribution during Apoptosis Process

We developed a microsystem for cell experiments consisting of a scanning thermal lens microscope detection system and a cell culture microchip. The microchip system was good for liquid control in microspace, and this results in secure cell stimulation and coincident in vivo observation of the cell r...

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Veröffentlicht in:	Analytical chemistry (Washington) 2002-04, Vol.74 (7), p.1560-1564
Hauptverfasser:	Tamaki, Eiichiro, Sato, Kiichi, Tokeshi, Manabu, Sato, Kae, Aihara, Makoto, Kitamori, Takehiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Apoptosis Chemical and thermal methods Chemistry Cytochrome c Group - analysis Cytochrome c Group - metabolism Cytological Techniques - instrumentation Cytoplasm - metabolism Exact sciences and technology Humans Microscopes Microscopy - instrumentation Microscopy - methods Miniaturization Mitochondria - metabolism Neuroblastoma - metabolism Neuroblastoma - pathology Neuroblastoma - ultrastructure Protein Transport
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