Mechanism of a model dipeptide transport across blood-ocular barriers following systemic administration

The purposes of this study were to provide functional evidence for the presence of a peptide transporter on blood-ocular barriers and to elucidate the mechanism of a dipeptide transport across these barriers following systemic administration. Glycylsarcosine was chosen as a model dipeptide and [ 3H]...

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Veröffentlicht in:	Experimental eye research 2004-04, Vol.78 (4), p.815-822
Hauptverfasser:	Atluri, Harisha, Anand, Banmeet S, Patel, Jignesh, Mitra, Ashim K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aqueous Humor - metabolism Biological Transport blood-aqueous barrier Blood-Aqueous Barrier - physiology blood-ocular barriers blood-retinal barrier Blood-Retinal Barrier - physiology dipeptide Dipeptides - pharmacokinetics Dose-Response Relationship, Drug glycylsarcosine Injections, Intravenous Male oligopeptide transporter Rabbits Retina - metabolism Time Factors Vitreous Body - metabolism
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