Riboflavin as a Determinant of Plasma Total Homocysteine: Effect Modification by the Methylenetetrahydrofolate Reductase C677T Polymorphism

Plasma total homocysteine (tHcy) is a risk factor for cardiovascular disease. tHcy concentrations are partly determined by folate, cobalamin, and vitamin B(6) status, and methylenetetrahydrofolate reductase (MTHFR) and other flavoenzymes are important for the biotransformation of these vitamins. Thi...

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Veröffentlicht in:	Clinical chemistry (Baltimore, Md.) Md.), 2000-08, Vol.46 (8), p.1065-1071
Hauptverfasser:	Hustad, Steinar, Ueland, Per Magne, Vollset, Stein Emil, Zhang, Ying, Bjorke-Monsen, Anne Lise, Schneede, Jorn
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Amino Acid Substitution Aminoacid disorders Biological and medical sciences Cross-Sectional Studies Electrophoresis, Capillary Errors of metabolism Female Folic Acid - blood Homocysteine - blood Humans Male Medical sciences Metabolic diseases Methylenetetrahydrofolate Reductase (NADPH2) Middle Aged Mutation Oxidoreductases Acting on CH-NH Group Donors - genetics Oxidoreductases Acting on CH-NH Group Donors - metabolism Polymorphism, Genetic Regression Analysis Riboflavin - blood
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