Guided tissue regeneration: porcine matrix does not transmit PERV

Objective: For cardiovascular tissue engineering, acellularized scaffolds of porcine matrices have been successfully used. However, the possibility of porcine endogenous retrovirus (PERV) transmission remains debatable. In this study, we investigated whether acellularized porcine vascular scaffolds...

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Veröffentlicht in:	Biomaterials 2004-08, Vol.25 (17), p.3613-3620
Hauptverfasser:	Kallenbach, Klaus, Leyh, Rainer G., Lefik, Elena, Walles, Thorsten, Wilhelmi, Matthias, Cebotari, Serghei, Schmiedl, Andreas, Haverich, Axel, Mertsching, Heike
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bioartificial Organs - adverse effects Bioartificial Organs - virology Bioartificial vessel grafts Cardiovascular Endogenous Retroviruses - isolation & purification Extracellular Matrix - transplantation Extracellular Matrix - virology Graft Rejection - diagnosis Graft Rejection - etiology Graft Rejection - virology Male PERV Porcine endogenous retrovirus Regeneration Retroviridae Infections - diagnosis Retroviridae Infections - transmission Retroviridae Infections - virology Swine Tissue engineering Tissue Engineering - adverse effects Tissue Engineering - methods Transplants - adverse effects
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