In Vivo RNA Interference Analysis Reveals an Unexpected Role for GNBP1 in the Defense against Gram-positive Bacterial Infection in Drosophila Adults

The Drosophila immune system discriminates between different classes of infectious microbes and responds with pathogen-specific defense reactions via the selective activation of the Toll and the immune deficiency (Imd) signaling pathways. The Toll pathway mediates most defenses against Gram-positive...

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Veröffentlicht in:	The Journal of biological chemistry 2004-03, Vol.279 (13), p.12848-12853
Hauptverfasser:	Pili-Floury, Sebastien, Leulier, François, Takahashi, Kuniaki, Saigo, Kaoru, Samain, Emmanuel, Ueda, Ryu, Lemaitre, Bruno
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacteria Carrier Proteins - chemistry Carrier Proteins - genetics Carrier Proteins - physiology Drosophila Drosophila - microbiology Drosophila Proteins - chemistry Drosophila Proteins - genetics Drosophila Proteins - metabolism Drosophila Proteins - physiology Gene Silencing Genetic Predisposition to Disease Gram-Positive Bacterial Infections - prevention & control Peptides - chemistry Phenotype Receptors, Cell Surface - metabolism Reverse Transcriptase Polymerase Chain Reaction RNA Interference RNA, Double-Stranded - biosynthesis Signal Transduction Time Factors Toll-Like Receptors
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