Transverse myelitis associated with restless legs syndrome and periodic movements of sleep responsive to an oral dopaminergic agent but not to intrathecal baclofen
Periodic limb movement disorder (PLMD) and restless legs syndrome (RLS) are related sleep disorders that occur with increased frequency in spinal cord disease. Effective treatment may be obtained with dopaminergic or opioid drugs, while anticonvulsants, benzodiazepines, and possibly baclofen may be...
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Veröffentlicht in: | Sleep (New York, N.Y.) N.Y.), 2000-08, Vol.23 (5), p.591-594 |
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description | Periodic limb movement disorder (PLMD) and restless legs syndrome (RLS) are related sleep disorders that occur with increased frequency in spinal cord disease. Effective treatment may be obtained with dopaminergic or opioid drugs, while anticonvulsants, benzodiazepines, and possibly baclofen may be helpful. This report describes a patient who developed RLS and PLMD after acute transverse myelitis associated with infectious mononucleosis, and failed to respond to intrathecal baclofen. All symptoms of RLS/PLMD resolved after treatment with pergolide. |
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All symptoms of RLS/PLMD resolved after treatment with pergolide.</description><identifier>ISSN: 0161-8105</identifier><identifier>EISSN: 1550-9109</identifier><identifier>PMID: 10947026</identifier><identifier>CODEN: SLEED6</identifier><language>eng</language><publisher>Rochester, MN: American Academy of Sleep Medicine</publisher><subject>Acute Disease ; Antiparkinson Agents - administration & dosage ; Antiparkinson Agents - therapeutic use ; Baclofen - administration & dosage ; Baclofen - therapeutic use ; Biological and medical sciences ; Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes ; Electromyography ; Electrooculography ; Humans ; Injections, Spinal ; Male ; Medical sciences ; Middle Aged ; Muscle Relaxants, Central - administration & dosage ; Muscle Relaxants, Central - therapeutic use ; Myelitis, Transverse - complications ; Myelitis, Transverse - drug therapy ; Nervous system (semeiology, syndromes) ; Neurology ; Nocturnal Myoclonus Syndrome - diagnosis ; Nocturnal Myoclonus Syndrome - drug therapy ; Nocturnal Myoclonus Syndrome - etiology ; Pergolide - administration & dosage ; Pergolide - therapeutic use ; Polysomnography ; Restless Legs Syndrome - diagnosis ; Restless Legs Syndrome - drug therapy ; Restless Legs Syndrome - etiology ; Sleep, REM - physiology ; Treatment Outcome</subject><ispartof>Sleep (New York, N.Y.), 2000-08, Vol.23 (5), p.591-594</ispartof><rights>2001 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=796003$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10947026$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>BROWN, L. K</creatorcontrib><creatorcontrib>HEFFNER, J. E</creatorcontrib><creatorcontrib>OBBENS, E. A. M. T</creatorcontrib><title>Transverse myelitis associated with restless legs syndrome and periodic movements of sleep responsive to an oral dopaminergic agent but not to intrathecal baclofen</title><title>Sleep (New York, N.Y.)</title><addtitle>Sleep</addtitle><description>Periodic limb movement disorder (PLMD) and restless legs syndrome (RLS) are related sleep disorders that occur with increased frequency in spinal cord disease. Effective treatment may be obtained with dopaminergic or opioid drugs, while anticonvulsants, benzodiazepines, and possibly baclofen may be helpful. This report describes a patient who developed RLS and PLMD after acute transverse myelitis associated with infectious mononucleosis, and failed to respond to intrathecal baclofen. All symptoms of RLS/PLMD resolved after treatment with pergolide.</description><subject>Acute Disease</subject><subject>Antiparkinson Agents - administration & dosage</subject><subject>Antiparkinson Agents - therapeutic use</subject><subject>Baclofen - administration & dosage</subject><subject>Baclofen - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes</subject><subject>Electromyography</subject><subject>Electrooculography</subject><subject>Humans</subject><subject>Injections, Spinal</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Muscle Relaxants, Central - administration & dosage</subject><subject>Muscle Relaxants, Central - therapeutic use</subject><subject>Myelitis, Transverse - complications</subject><subject>Myelitis, Transverse - drug therapy</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Neurology</subject><subject>Nocturnal Myoclonus Syndrome - diagnosis</subject><subject>Nocturnal Myoclonus Syndrome - drug therapy</subject><subject>Nocturnal Myoclonus Syndrome - etiology</subject><subject>Pergolide - administration & dosage</subject><subject>Pergolide - therapeutic use</subject><subject>Polysomnography</subject><subject>Restless Legs Syndrome - diagnosis</subject><subject>Restless Legs Syndrome - drug therapy</subject><subject>Restless Legs Syndrome - etiology</subject><subject>Sleep, REM - physiology</subject><subject>Treatment Outcome</subject><issn>0161-8105</issn><issn>1550-9109</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo90NtKAzEQBuBFFFsPryABwbuFZDdpdi9FPIHgTb0uOczWSDZZM2mlz-OLmmL1ahjm-wdmjqo5E4LWPaP9cTWnbMHqjlExq84QP2jped-eVrMy5pI2i3n1vUwq4BYSAhl34F12SBRiNE5lsOTL5XeSALMHROJhjQR3waY4AlHBkgmSi9YZMsYtjBAykjgQ9ADTPjbFgG4LJMeiSUzKExsnNboAaV1Sal0iRG8yCTHvlQs5qfwOpkitjI8DhIvqZFAe4fJQz6u3h_vl3VP98vr4fHf7Uk9NK3INmva25UqwRnA5dN3CNmC5krphHeiBD9QIaalsQAltNROGU0aNtj1YbWV7Xt387p1S_NyUm1ejQwPeqwBxgyvJJOd9xwq8OsCNHsGupuRGlXarv7cWcH0ACsslQ_mxcfjvZL-gtG1_ADX2huY</recordid><startdate>20000801</startdate><enddate>20000801</enddate><creator>BROWN, L. 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T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p235t-eb09d34a512547f886d2ed4a7b218ebf4f0c57d072ea5bdb15c4010cbd9edbd73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Acute Disease</topic><topic>Antiparkinson Agents - administration & dosage</topic><topic>Antiparkinson Agents - therapeutic use</topic><topic>Baclofen - administration & dosage</topic><topic>Baclofen - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes</topic><topic>Electromyography</topic><topic>Electrooculography</topic><topic>Humans</topic><topic>Injections, Spinal</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Muscle Relaxants, Central - administration & dosage</topic><topic>Muscle Relaxants, Central - therapeutic use</topic><topic>Myelitis, Transverse - complications</topic><topic>Myelitis, Transverse - drug therapy</topic><topic>Nervous system (semeiology, syndromes)</topic><topic>Neurology</topic><topic>Nocturnal Myoclonus Syndrome - diagnosis</topic><topic>Nocturnal Myoclonus Syndrome - drug therapy</topic><topic>Nocturnal Myoclonus Syndrome - etiology</topic><topic>Pergolide - administration & dosage</topic><topic>Pergolide - therapeutic use</topic><topic>Polysomnography</topic><topic>Restless Legs Syndrome - diagnosis</topic><topic>Restless Legs Syndrome - drug therapy</topic><topic>Restless Legs Syndrome - etiology</topic><topic>Sleep, REM - physiology</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>BROWN, L. K</creatorcontrib><creatorcontrib>HEFFNER, J. E</creatorcontrib><creatorcontrib>OBBENS, E. A. M. T</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Sleep (New York, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>BROWN, L. K</au><au>HEFFNER, J. E</au><au>OBBENS, E. A. M. T</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Transverse myelitis associated with restless legs syndrome and periodic movements of sleep responsive to an oral dopaminergic agent but not to intrathecal baclofen</atitle><jtitle>Sleep (New York, N.Y.)</jtitle><addtitle>Sleep</addtitle><date>2000-08-01</date><risdate>2000</risdate><volume>23</volume><issue>5</issue><spage>591</spage><epage>594</epage><pages>591-594</pages><issn>0161-8105</issn><eissn>1550-9109</eissn><coden>SLEED6</coden><abstract>Periodic limb movement disorder (PLMD) and restless legs syndrome (RLS) are related sleep disorders that occur with increased frequency in spinal cord disease. Effective treatment may be obtained with dopaminergic or opioid drugs, while anticonvulsants, benzodiazepines, and possibly baclofen may be helpful. This report describes a patient who developed RLS and PLMD after acute transverse myelitis associated with infectious mononucleosis, and failed to respond to intrathecal baclofen. All symptoms of RLS/PLMD resolved after treatment with pergolide.</abstract><cop>Rochester, MN</cop><pub>American Academy of Sleep Medicine</pub><pmid>10947026</pmid><tpages>4</tpages></addata></record> |
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source | MEDLINE; Oxford University Press Journals All Titles (1996-Current); EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
subjects | Acute Disease Antiparkinson Agents - administration & dosage Antiparkinson Agents - therapeutic use Baclofen - administration & dosage Baclofen - therapeutic use Biological and medical sciences Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes Electromyography Electrooculography Humans Injections, Spinal Male Medical sciences Middle Aged Muscle Relaxants, Central - administration & dosage Muscle Relaxants, Central - therapeutic use Myelitis, Transverse - complications Myelitis, Transverse - drug therapy Nervous system (semeiology, syndromes) Neurology Nocturnal Myoclonus Syndrome - diagnosis Nocturnal Myoclonus Syndrome - drug therapy Nocturnal Myoclonus Syndrome - etiology Pergolide - administration & dosage Pergolide - therapeutic use Polysomnography Restless Legs Syndrome - diagnosis Restless Legs Syndrome - drug therapy Restless Legs Syndrome - etiology Sleep, REM - physiology Treatment Outcome |
title | Transverse myelitis associated with restless legs syndrome and periodic movements of sleep responsive to an oral dopaminergic agent but not to intrathecal baclofen |
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