The Tim8-Tim13 Complex of Neurospora crassa Functions in the Assembly of Proteins into Both Mitochondrial Membranes

The Tim8 and Tim13 proteins in yeast are known to exist in the mitochondrial intermembrane space and to form a hetero-oligomeric complex involved in the import of the mitochondrial inner membrane protein Tim23, the central component of the TIM23 translocase. Here, we have isolated tim8 and tim13 mut...

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Veröffentlicht in:	The Journal of biological chemistry 2004-03, Vol.279 (13), p.12396-12405
Hauptverfasser:	Hoppins, Suzanne C., Nargang, Frank E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Carrier Proteins - physiology Cell Membrane - metabolism Cross-Linking Reagents - pharmacology Electrophoresis, Polyacrylamide Gel Intracellular Membranes - metabolism Membrane Potentials Membrane Transport Proteins - physiology Mitochondria - metabolism Mitochondrial Membrane Transport Proteins Mitochondrial Proteins - physiology Molecular Sequence Data Mutation Neurospora crassa Neurospora crassa - metabolism Plasmids - metabolism Point Mutation Porins - chemistry Protein Binding Protein Structure, Secondary Protein Transport Saccharomyces cerevisiae Proteins - physiology Sequence Homology, Amino Acid Subcellular Fractions - metabolism Temperature Tim13 protein Tim8 protein Tom40 protein
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